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| Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate Basic information |
| Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate Chemical Properties |
Melting point | 253-254 °C | Boiling point | 76-78°C 0,5mm | density | 1.491 | refractive index | n20/D1.468 | Fp | >110℃ | storage temp. | 2-8°C | pka | -5.70±0.29(Predicted) | CAS DataBase Reference | 175137-27-6(CAS DataBase Reference) |
| Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate Usage And Synthesis |
Uses | Methyl 2-Chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate is used in the synthetic preparation and discovery of 2-[(2,4-Dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide (G931520) which is a highly selective CB2 receptor agonist for the treatment of inflammatory and neuropathic pain. |
| Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate Preparation Products And Raw materials |
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