- Tamsulosin hydrochloride
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- $99.99 / 10g
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2022-02-24
- CAS:80223-99-0
- Min. Order: 10g
- Purity: 99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets,Customiz
- Supply Ability: 1000kgs
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| Tamsulosin hydrochloride Basic information |
| Tamsulosin hydrochloride Chemical Properties |
Melting point | 254-256 °C | solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| Tamsulosin hydrochloride Usage And Synthesis |
Chemical Properties | White to Off-White Solid | Uses | Tamsulosin hydrochloride is a specific ;1-adrenoceptor antagonist. Used in the treatment of benign prostatic hypertrophy. | Uses | Tamsulosin is a specific α1-adrenoceptor antagonist. Used in the treatment of benign prostatic hypertrophy. | Clinical Use | Treatment of benign prostatic hyperplasia | Drug interactions | Potentially hazardous interactions with other drugs
Anaesthetics: enhanced hypotensive effect.
Antidepressants: enhanced hypotensive effect with
MAOIs.
Antifungals: concentration increased by
ketoconazole.
Avanafil, vardenafil, sildenafil and tadalafil: enhanced
hypotensive effect, avoid concomitant use.
Beta-blockers: enhanced hypotensive effect;
increased risk of first dose hypotensive effect.
Calcium-channel blockers: enhanced hypotensive
effect; increased risk of first dose hypotensive effect.
Diuretics: enhanced hypotensive effect; increased
risk of first dose hypotensive effect.
Moxisylyte: possibly severe postural hypotension. | Metabolism | Tamsulosin is metabolised slowly in the liver primarily
by the cytochrome P450 isoenzymes CYP2D6 and
CYP3A4; it is excreted mainly in the urine as metabolites
and some unchanged drug |
| Tamsulosin hydrochloride Preparation Products And Raw materials |
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