| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
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| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:JNK-IN-11
CAS:676594-38-0
Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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| Company Name: |
Bide Pharmatech Ltd.
|
| Tel: |
400-1647117 13681763483 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:Methyl 3-(2-(thiophen-2-yl)acetamido)thiophene-2-carboxylate
CAS:676594-38-0
Purity:97% Package:10mg;25mg;50mg;100mg;250mg Remarks:BD01318135
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:JNK-IN-11
CAS:676594-38-0
Purity:95% Package:1mg;5mg;10mg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:JNK-IN-11
CAS:676594-38-0
Purity:98.82% Package:1mg/RMB 378;5mg/RMB 892;10mg/RMB 1450
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2-Thiophenecarboxylic acid, 3-[[2-(2-thienyl)acetyl]amino]-, methyl ester manufacturers
- JNK-IN-11
-
- $39.00 / 1mg
-
2025-11-10
- CAS:676594-38-0
- Min. Order:
- Purity: 98.82%
- Supply Ability: 10g
|
| | 2-Thiophenecarboxylic acid, 3-[[2-(2-thienyl)acetyl]amino]-, methyl ester Basic information |
| | 2-Thiophenecarboxylic acid, 3-[[2-(2-thienyl)acetyl]amino]-, methyl ester Chemical Properties |
| Boiling point | 510.5±50.0 °C(Predicted) | | density | 1.406±0.06 g/cm3(Predicted) | | pka | 13.59±0.70(Predicted) | | form | Solid | | color | White to yellow |
| | 2-Thiophenecarboxylic acid, 3-[[2-(2-thienyl)acetyl]amino]-, methyl ester Usage And Synthesis |
| Uses | JNK-IN-11 (compound 1) is a potent JNK inhibitor with an IC50 value of 2.2, 21.4, 1.8 μM for JNK1, JNK2, JNK3, respectively. JNK-IN-11 has the potential for the research of alzheimer and parkinson disease[1]. | | Definition | ChEBI: Methyl 3-[2-(2-thienyl)acetamido]thiophene-2-carboxylate is a carboxamide resulting from the formal condensation of the carboxy group of 2-thienylacetic acid with the amino group of methyl 3-aminothiophene-2-carboxylate. It is a selective inhibitor of c-Jun N-terminal kinases (JNKs). It has a role as a c-Jun N-terminal kinase inhibitor. It is a methyl ester, a member of thiophenes and a secondary carboxamide. It is functionally related to a 2-thienylacetic acid. | | IC 50 | JNK1: 1.8 μM (IC50); JNK3: 2.2 μM (IC50); JNK2: 21.4 μM (IC50) | | References | [1] Hom RK, et al. Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7303-7. DOI:10.1016/j.bmcl.2010.10.066 |
| | 2-Thiophenecarboxylic acid, 3-[[2-(2-thienyl)acetyl]amino]-, methyl ester Preparation Products And Raw materials |
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