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| diphyllin Basic information |
Product Name: | diphyllin | Synonyms: | 4-Hydroxy-6,7-dimethoxy-9-(1,3-benzodioxole-5-yl)-1,3-dihydronaphtho[2,3-c]furan-1-one;9-(1,3-Benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxynaphtho[2,3-c]furan-1(3H)-one;Diphyllin【naphthofuran】;NSC 309691;Diphyllin >=98% (HPLC);9-(1,3-benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-3H-benzo[f][2]benzofuran-1-one;Phyllis;Naphtho[2,3-c]furan-1(3H)-one, 9-(1,3-benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy- | CAS: | 22055-22-7 | MF: | C21H16O7 | MW: | 380.35 | EINECS: | | Product Categories: | | Mol File: | 22055-22-7.mol | |
| diphyllin Chemical Properties |
Melting point | 290℃ (methanol ) | Boiling point | 638.8±55.0 °C(Predicted) | density | 1.445±0.06 g/cm3 (20 ºC 760 Torr) | storage temp. | 2-8°C | solubility | Soluble in DMSO | pka | 7.82±0.20(Predicted) | form | powder | color | white to light brown |
| diphyllin Usage And Synthesis |
Uses | Diphyllin has been used to study its antibacterial and antibiofilm activities against fish pathogens. | Definition | ChEBI: Diphyllin is a lignan. | General Description | Diphyllin, a major glycoside compound, is a plant-derived lignan. It is present in Cleistanthus collinus. | Biochem/physiol Actions | Diphyllin is a natural arylnaphthalene that exhibits potent anticancer and antiviral activities. It is a potent inhibitor of vacuolar H(+)-ATPase (V-ATPase) that inhibits lysosomal acidification in osteoclasts. |
| diphyllin Preparation Products And Raw materials |
Raw materials | 2,3-Naphthalenedicarboxylic acid, 1-(1,3-benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-, 2,3-diethyl ester-->Naphtho[2,3-c]furan-1,4-dione, 9-(1,3-benzodioxol-5-yl)-3,3a,9,9a-tetrahydro-9-hydroxy-6,7-dimethoxy-, [3aS-(3aα,9α,9aα)]- (9CI)-->9-(benzo[d][1,3]dioxol-5-yl)-6,7-dimethoxy-1-oxo-1,3-dihydronaphtho[2,3-c]furan-4-yl acetate-->6-Bromoveratraldehyde-->Diethyl ether | Preparation Products | justicidin A |
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