Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037 |
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3bsc@sina.com |
Products Intro: |
Product Name:Y 134;[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl]-[4-[4-(1-Methylethyl)-1-piperazinyl]phenyl]Methanone CAS:849662-80-2 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Company Name: |
BOC Sciences
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Tel: |
1-631-485-4226; 16314854226 |
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info@bocsci.com |
Products Intro: |
Product Name:Y 134 CAS:849662-80-2 Purity:98% by HPLC Remarks:Y 134 is a selective estrogen receptor modulator (SERM) with selectivity for ERα over ERβ (Ki = 0.09 and 11.31 nM, respectively). It has no cross-reactivity with mineralocorticoid, glucocorticoid, and
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Company Name: |
EMMX Biotechnology LLC
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888-539-0666 |
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info@emmx.com |
Products Intro: |
Product Name:Y 134 CAS:849662-80-2 Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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Product Name: | Y 134 | Synonyms: | Y 134;[6-HYDROXY-2-(4-HYDROXYPHENYL)BENZO[B]THIEN-3-YL]-[4-[4-(1-METHYLETHYL)-1-PIPERAZINYL]PHENYL]METHANONE;Methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[4-(1-methylethyl)-1-piperazinyl]phenyl]-;Y-134,Y134 | CAS: | 849662-80-2 | MF: | C28H28N2O3S | MW: | 472.6 | EINECS: | | Product Categories: | | Mol File: | 849662-80-2.mol | |
| Y 134 Chemical Properties |
storage temp. | Desiccate at RT | solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol | form | Powder |
| Y 134 Usage And Synthesis |
Uses | Y 134 is a SERM displaying selectivity for ERα over ERβ. | Definition | ChEBI: [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(4-propan-2-yl-1-piperazinyl)phenyl]methanone is an aromatic ketone. | Biological Activity | Selective estrogen receptor modulator (SERM) that displays selectivity for ER α over ER β (K i values are 0.09 and 11.31 nM respectively) and no cross-reactivity with mineralocorticoid, glucocorticoid, androgen and progesterone receptors. Acts as an agonist in the bone and antagonist in reproductive tissue. Suppresses estrogen-stimulated proliferation of ER-positive human breast cancer MCF-7 and T47D cells. | storage | Desiccate at RT |
| Y 134 Preparation Products And Raw materials |
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