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N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite

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N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite Suppliers list
Company Name: Shenzhen Nexconn Pharmatechs Ltd
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Products Intro: Product Name:2’-O-Propargyl-G(iBu)-3’-phosphoramidite
CAS:171486-61-6
Purity:98% Package:1KG;10KG;50KG
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Products Intro: Product Name:2'-O-Propargyl G(iBu)-3'-phosphoramidite
CAS:171486-61-6
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Products Intro: Product Name:N2-iBu-5'-O-DMTr-2'-O-propargylguanosine-3'-CED-phosphoramidite
CAS:171486-61-6
Purity:97% Package:mgs,gs,kgs
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Products Intro: Product Name:2'-O-Propargyl G(iBu)-3'-phosphoramidite
CAS:171486-61-6
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Products Intro: Product Name:(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
CAS:171486-61-6
Purity:99% Package:mg,g,kg

N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite manufacturers
N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite Basic information
Product Name:N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite
Synonyms:N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite;2'-O-Propargyl G(iBu)-3'-phosphoramidite;2’-O-Propargyl G(iBu)-3’-phosphoramidite, N2-iBu-5’-O-DMTr-2’-O-propargylguanosine-3’-CED-phosphoramidite;Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-2'-O-2-propynyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI);5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-2-propyn-1-ylguanosine;5'-O-DMT-N2-isobutyryl-2'-O-propynylguanosine 3'-CE phosphoramidite;N2-iBu-5’-O-DMTr-2’-O-propargylguanosine-3’-CED-phosphoramidite,2’-O-Propargyl-G(iBu)-3’-phosphoramidit;N2-iBu-5’-O-DMTr-2’-O-propargylguanosine-3’-CED-phosphoramidite
CAS:171486-61-6
MF:C47H56N7O9P
MW:893.96
EINECS:
Product Categories:2'-O-Propargyl
Mol File:171486-61-6.mol
N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite Structure
N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite Chemical Properties
pka9.16±0.20(Predicted)
Safety Information
MSDS Information
N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite Usage And Synthesis
UsesN2-iBu-5’-O-DMTr-2’-O-propargylguanosine-3’-CED-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
References[1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100
N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite Preparation Products And Raw materials
Tag:N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite(171486-61-6) Related Product Information
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