129280-22-4
| 中文名称 | 129280-22-4 |
|---|---|
| 中文同义词 | ANTI-HYPERTENSIVE SULFONANILIDE 1;化合物 T10511 |
| 英文名称 | Benzonitrile, 4-[2-(4,4-dimethyl-2-oxo-3-oxazolidinyl)-4-thiazolyl]-Methanesulfonamide, N-[4-[1-hydroxy-2-[[(1,2,3,4-tetrahydro-1-oxo-2-naphthalenyl)methyl]amino]ethyl]phenyl]-, hydrochloride |
| 英文同义词 | Benzonitrile, 4-[2-(4,4-dimethyl-2-oxo-3-oxazolidinyl)-4-thiazolyl]-Methanesulfonamide, N-[4-[1-hydroxy-2-[[(1,2,3,4-tetrahydro-1-oxo-2-naphthalenyl)methyl]amino]ethyl]phenyl]-, hydrochloride;Anti-hypertensive sulfonanilide 1;Antihypertensive sulfonanilide 1,Anti hypertensive sulfonanilide 1 |
| CAS号 | 129280-22-4 |
| 分子式 | C35H37ClN5O6S2 |
| 分子量 | 723.28118 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 129280-22-4.mol |
| 结构式 |  |
129280-22-4 性质
| 储存条件 | Store at -20°C |
|---|---|
| 溶解度 | 溶于二甲基亚砜 |
Anti-hypertensive sulfonanilide 1是有效抗高血压剂，来自专利 EP0338793A2，化合物 XVIIIa,b*，实例1。
Anti-hypertensive sulfonanilide 1 can be classified as tetralin sulfonanilides, is found to have antihypertensive properties and is therefore useful in controlling elevated blood pressure in mammals such as humans. The effective antihypertensive amount for use will vary both with the route of administration, the condition under treatment and the mammal undergoing treatment, and is ultimately at the discretion of the physician. A suitable oral dose of the active compound for a mammal is in the range of from about 1 to about 50 mg per kilogram body weight per day; preferably from about 2 to about 20 mg/kg.