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1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER

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1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER Suppliers list
Company Name: Chongqing Ensky Pharmaceutical Co.,Ltd.
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Products Intro: Product Name:1,4-Dihydro-2-(methylthio)-4-oxo-5-pyrimidine-carboxylateacidethylester
CAS:53554-29-3
Purity:0.99 Package:25KG;1KG
Company Name: Capot Chemical Co.,Ltd.
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Products Intro: Product Name:Ethyl 4-hydroxy-2-(methylthio)pyrimidine-5-carboxylate
CAS:53554-29-3
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: ATK CHEMICAL COMPANY LIMITED
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Products Intro: CAS:53554-29-3
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: career henan chemical co
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Products Intro: Product Name:1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER
CAS:53554-29-3
Purity:99% Package:1kg;1USD
Company Name: Accela ChemBio Inc.
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Products Intro: Product Name:Ethyl 4-Hydroxy-2-(methylthio)pyrimidine-5-carboxylate
CAS:53554-29-3
Purity:>97% Package:25g;100g Remarks:SY018371

1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER manufacturers
1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER Basic information
Product Name:1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER
Synonyms:1,4-Dihydro-2-(methylthio)-4-oxo-5-pyrimidine-1,4-Dihydro-2-(methylthio)-4-oxo-5-pyrimidine-;5-PyriMidinecarboxylicacid, 1,6-dihydro-2-(Methylthio)-6-oxo-, ethyl ester;Ethyl 2-Methylsulfanyl-6-oxo-1h-pyriMidine-5-carboxylate;Ethyl 2-(Methylthio)-6-oxo-1,6-dihydropyriMidine-5-carboxylate;1,4-dihydro-2-Methyl-4-oxo-5-Mercapto-pyriMidine-carboxylic acid ethyl ester;Ethyl 2-(methylsulfanyl)-4-oxo-1,4-dihydropyrimidine-5-carboxylate;1,4-Dihydro-2-(methylthio)-4-oxo-5-pyrimidine-;1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINECARBOXYLIC ACID ETHYL ESTER >98%
CAS:53554-29-3
MF:C8H10N2O3S
MW:214.24
EINECS:
Product Categories:pyrimidine
Mol File:53554-29-3.mol
1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER Structure
1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER Chemical Properties
Melting point 136-144°C
density 1.37±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka6.48±0.50(Predicted)
CAS DataBase Reference53554-29-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
HazardClass IRRITANT
HS Code 2933599590
MSDS Information
1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER Usage And Synthesis
Uses1,4-Dihydro-2-methylmercapto-4-oxo-5-pyrimidinecarboxylic acid ethyl ester can be used as several synthetic intermediates and pharmaceutical intermediates, mainly used in laboratory research and development process and pharmaceutical and chemical production process.
SynthesisMethylthiourea sulfate (75.2g, 0.4mol) was added to 16% NaOH (250mL, 1.18mol) solution and stirred for 30min, then diethyl ethoxymethylenemalonate (103.4g, 0.48 mol) was dissolved in 160 mL of ethanol and slowly dropped into the reaction solution. After the dropwise addition was completed, the reaction was carried out at room temperature for 10 h.When a large amount of white solid was precipitated, carry out suction filtration, wash with water, and vacuum dry to obtain a white solid (84.7g, 99.7%); ESE-MS (m/z): 249[M+H]+, 236.9[M+Na]+ , after verification, the product is 1,4-dihydro-2-methylmercapto-4-oxo-5-pyrimidinecarboxylic acid ethyl ester.
Tag:1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER(53554-29-3) Related Product Information
1,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-5-PYRIMIDINE-CARBOXYLATE ACID ETHYL ESTER ETHYL 5-PYRIMIDINECARBOXYLATE 98 ETHYL 2-(METHYLSULFANYL)-4-[3-(TRIFLUOROMETHYL)PHENOXY]-5-PYRIMIDINECARBOXYLATE Avanafil Impurity 9 Avanafil Impurity 19 Avanafil Impurity 24 4-(4-MethoxybenzylaMino)-5-ethoxycarbonyl-2-MethylthiopyriMidine Avanafil Impurity 10 Avanafil Impurity 16 Avanafil Impurity 26 1364671-52-2 5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]- Avanafil iMpurity 5 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid Avanafil Impurity 23 Avanafil iMpurity 2 Avanafil Impurity 20 Avanafil Impurity 25