C6 L-erythro Ceramide (d18:1/6:0)

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CAS:189894-78-8
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Products Intro: Product Name:C6 L-erythro Ceramide (d18:1/6:0)
CAS:189894-78-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
C6 L-erythro Ceramide (d18:1/6:0) Basic information
Product Name:C6 L-erythro Ceramide (d18:1/6:0)
Synonyms:C6 L-erythro Ceramide (d18:1/6:0);Hexanoyl-L-erythro-sphingosine;Hexanamide, N-[(1R,2S,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-;N-[(1R,2S,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-hexanamide
CAS:189894-78-8
MF:C24H47NO3
MW:397.63
EINECS:
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Mol File:189894-78-8.mol
C6 L-erythro Ceramide (d18:1/6:0) Structure
C6 L-erythro Ceramide (d18:1/6:0) Chemical Properties
Boiling point 574.7±50.0 °C(Predicted)
density 0.946±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Chloroform: Soluble; DMF: 5 mg/ml; DMSO: Soluble; Ethanol: Soluble
form A solid
pka13.53±0.20(Predicted)
Safety Information
MSDS Information
C6 L-erythro Ceramide (d18:1/6:0) Usage And Synthesis
DescriptionC6 L-erythro Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.1,2 It is metabolized by ceramide glucosyltransferase to form C6 L-erythro glucosylceramide. C6 L-erythro Ceramide is cytotoxic to U937 cells (IC50 = 18 μM).3
References1. Schwarz, A., and Futerman, A.H. Distinct roles for ceramide and glucosylceramide at different stages of neuronal growth J. Neurosci. 17(9),2929-2938(1997).
2. Paul, P., Kamisaka, Y., Marks, D.L., et al. Purification and characterization of UDP-glucose: Ceramide glucosyltransferase from rat liver Golgi membranes Curr. Opin. Struct. Biol. 271(4),2287-2293(1996).
3. Chang, Y.-T., Choi, J., Ding, S., et al. The synthesis and biological characterization of a ceramide library J. Am. Chem. Soc. 124(9),1856-1857(2002).
C6 L-erythro Ceramide (d18:1/6:0) Preparation Products And Raw materials
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