AMYLIN拮抗剂多肽AC 253
| 中文名称 | AMYLIN拮抗剂多肽AC 253 |
|---|---|
| 中文同义词 | AMYLIN拮抗剂多肽AC 253 |
| 英文名称 | AC253 |
| 英文同义词 | AC253;L-Tyrosinamide, N-acetyl-L-leucylglycyl-L-arginyl-L-leucyl-L-seryl-L-glutaminyl-L-α-glutamyl-L-leucyl-L-histidyl-L-arginyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparaginyl-L-threonylglycyl-L-seryl-L-asparaginyl-L-threonyl- (9CI) |
| CAS号 | 151804-79-4 |
| 分子式 | C122H196N40O39 |
| 分子量 | 2847.15 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 151804-79-4.mol |
| 结构式 |  |
AMYLIN拮抗剂多肽AC 253 性质
| 密度 | 1.53±0.1 g/cm3(Predicted) |
|---|
AC 253 is an Amylin (AMY3) receptor antagonist, inhibiting andrenomedulin-stimulated cAMP production. AC 253 protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death in neuronal cell culture. AC 253 blocks electrophysiological effects of Aβ.