胃动素
| 中文名称 | 胃动素 |
|---|---|
| 中文同义词 | 胃动素;胃动素,猪;胃动素,猪, ≥97% (HPLC);胃动素 (人类,猪);化合物MOTILIN (26-47), HUMAN, PORCINE;ANTI-MOTILIN ANTIBODY-胃动素抗体;胃动素 (人类,猪)、MOTILIN, HUMAN, PORCINE;猪胃动素 |
| 英文名称 | MOTILIN (HUMAN, PORCINE) |
| 英文同义词 | PHE-VAL-PRO-ILE-PHE-THR-TYR-GLY-GLU-LEU-GLN-ARG-MET-GLN-GLU-LYS-GLU-ARG-ASN-LYS-GLY-GLN;MOTILIN, PORCINE;H-PHE-VAL-PRO-ILE-PHE-THR-TYR-GLY-GLU-LEU-GLN-ARG-MET-GLN-GLU-LYS-GLU-ARG-ASN-LYS-GLY-GLN-OH;FVPIFTYGELQRMQEKERNKGQ;GASTRIC MOTOR STIMULATORY PEPTIDE, PORCINE;motilin;MOTILIN PORCINE ≥97%;Gastricmotorstimulatorypeptide |
| CAS号 | 52906-92-0 |
| 分子式 | C120H188N34O35S |
| 分子量 | 2699.05 |
| EINECS号 | |
| 相关类别 | 生化试剂;其他生化试剂;Peptide;LH-RH;LH-RHPeptides for Cell Biology;Neuropeptides;Releasing Factors;Various peptides |
| Mol文件 | 52906-92-0.mol |
| 结构式 |  |
胃动素 性质
| 储存条件 | −20°C |
|---|---|
| 溶解度 | 25mg/mL，溶于 DMSO 和 DMF，微溶于乙醇 |
| 形态 | 固体 |
| 颜色 | 白色至米白色 |
| 水溶解性 | Soluble to 1 mg/ml in water |
| 序列 | Phe-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Met-Gln-Glu-Lys-Glu-Arg-Asn-Lys-Gly-Gln |
EC50: 0.3 nM (motilin receptor, Chinese hamster ovary cell)
Ki: 2.3 nM (motilin receptor, Chinese hamster ovary cell)
[Bpa 1 ,Ile 13 ]motilin is a full agonist at the motilin receptor that increases intracellular calcium in a concentration-dependent manner (EC 50 = 1.5 ± 0.4 nM). Motilin binds with high affinity (IC 50 0.7± 0.2 nM) to receptors on smooth muscle cells. Motilin selectively activates G(q) and G(13), stimulates G alpha(q)-dependent phosphoinositide (PI) hydrolysis and 1,4,5-trisphosphate (IP(3))-dependent Ca 2+ release, and increases cytosolic free Ca 2+ . Motilin induces a biphasic, concentration-dependent contraction (EC 50 = 1.0 +/- 0.2 nM), consisting of an initial peak followed by a sustained contraction.
安全信息
| WGK Germany | 3 |
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| 提供商 | 语言 |
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英文
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| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/05/22 | HY-P1037 | 胃动素 Motilin (26-47), human, porcine | 52906-92-0 | 500μg | 580元 |
| 2025/05/22 | HY-P1037 | 胃动素 Motilin (26-47), human, porcine | 52906-92-0 | 1mg | 923元 |