ACTH (18-39) (HUMAN)
| 中文名称 | ACTH (18-39) (HUMAN) |
|---|---|
| 中文同义词 | 人ACTH (18-39)肽;RF-22;人促肾上腺皮质激素18-39;PERFEMIKER]人促肾上腺皮质激素18-39,95%;ACTH(18-39)(人类)TFA盐 |
| 英文名称 | CLIP |
| 英文同义词 | ACTH (18-39) (huMan) Corticotropin-Like InterMediate Peptide (CLIP);Corticotropin-Like InterMediate Peptide (CLIP);ProteoMass(R) ACTH FragMent 18-39 MALDI-MS Standard;ProteoMass? ACTH Fragment 18-39 MALDI-MS Standard;corticotropin-likeintermediatelobepeptide;H-ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE-OH;CLIP (HUMAN);CLIP |
| CAS号 | 53917-42-3 |
| 分子式 | C112H165N27O36 |
| 分子量 | 2465.67 |
| EINECS号 | |
| 相关类别 | 多肽;目录多肽;Peptide |
| Mol文件 | 53917-42-3.mol |
| 结构式 |  |
ACTH (18-39) (HUMAN) 性质
| 密度 | 1.49±0.1 g/cm3(Predicted) |
|---|---|
| 储存条件 | -20°C |
| 溶解度 | DMF：2.5mg/mL；二甲基亚砜：5mg/mL； PBS（pH 7.2）：5mg/mL |
| 形态 | 固体 |
| 序列 | H-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH |
The ACTH family of polypeptides consists of ACTH(1-39) (adrenocorticotropin), ACTH (1-13)amide (α-melanotropin;α-MSH); and ACTH (18-39) (corticotropinlike intermediate lobe peptide, CLIP). These polypeptides are derived from a common precursor, proopiomelanocortin. In corticotropic cells of the pars distalis, proopiomelanocortin (POMC) undergoes a series of proteolytic cleavage reactions to yield ACTH (1-39) as a major end product. However, in the melanotropic cells of the pars intermedia, an additional set of proteolytic reactions results in the conversion of ACTH (1-39) to ACTH (1-13) amide and ACTH (18-39). In several species of vertebrates, ACTH (1-13) amide undergoes end product modification to yield mono- and diacetylated forms ofα-MSH as major end products in the pars intermedia.
纯度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
内毒素≤50EU/mg
氨基酸组成分析≤±10%
安全信息
| WGK Germany | 3 |
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| 提供商 | 语言 |
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英文
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