(9E)-9-十六烯酸
中文名称 | (9E)-9-十六烯酸 |
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中文同义词 | (9E)-9-十六烯酸;反式-9-十六碳烯酸;十六碳烯酸(反-9);反式-棕榈油酸;棕榈酸酯?;(E)-9-十六烯酸 |
英文名称 | PALMITELAIDIC ACID |
英文同义词 | (9E)-9-Hexadecenoicacid;(e)-9-hexadecenoicaci;TRANS-9-HEXADECENOIC ACID;C16:1 (TRANS-9) ACID;DELTA 9 TRANS HEXADECENOIC ACID;PALMITELAIDIC ACID 99%;(E)-9-Hexadecenoicacid;9-Hexadecenoic acid, (9E)- |
CAS号 | 10030-73-6 |
分子式 | C16H30O2 |
分子量 | 254.41 |
EINECS号 | |
相关类别 | 脂肪酸 |
Mol文件 | 10030-73-6.mol |
结构式 |
(9E)-9-十六烯酸 性质
熔点 | 33-34℃ |
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沸点 | 374.4°C (estimate) |
密度 | 0.8855 (rough estimate) |
折射率 | 1.4501 (589.3 nm 40℃) |
储存条件 | Amber Vial, Refrigerator |
溶解度 | 可溶于DMSO(少量)、甲醇(少量) |
酸度系数(pKa) | 4.78±0.10(Predicted) |
形态 | 液体 |
颜色 | 白色至类白色 |
LogP | 6.635 (est) |
EPA化学物质信息 | 9-Hexadecenoic acid, (9E)- (10030-73-6) |
AMPK
|
PPARα
|
Glucokinase
|
The monounsaturated fatty acid palmitoleate (palmitoleic acid) is one of the most abundant fatty acids in serum and tissues, particularly adipose tissue and liver. Its endogenous production by stearoyl-CoA desaturase 1 gives rise to its cis isoform, cis-palmitoleate. Palmitoleic acid has been correlated with multiple cardiometabolic risk factors, including high blood pressure, total cholesterol, TGs, apoA-I, apoB, and endothelial dysfunction.
Palmitoleic acid promotes a faster uptake of glucose in the body, associated with higher insulin concentration. Palmitoleic acid increases the phosphorylation of AMPK, up-regulates glucokinase and down-regulates SREBP-1. Regarding AMPK downstream, palmitoleic acid increases the production of FGF-21 and stimulates the expression of PPARα. Palmitoleic acid reduces body weight increase, ameliorates the development of hyperglycemia and hypertriglyceridemia, and improves insulin sensitivity. Furthermore, palmitoleic acid down-regulates mRNA expressions of proinflammatory adipocytokine genes (TNFα and resistin) in white adipose tissue and lipogenic genes (SREBP-1, FAS, and SCD-1) in liver.
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/08/19 | HY-N2341 | (9E)-9-十六烯酸 Palmitelaidic Acid | 10030-73-6 | 10mg(393mM * 100μL in Ethanol) | 500元 |
2024/08/19 | HY-N2341 | Palmitelaidic Acid | 25 mg (393 mM * 250 μL in Ethanol) | 1000元 |