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ALOGLIPTIN(ALOGLIPTINE, ALOGLIPTINA)

ALOGLIPTIN(ALOGLIPTINE, ALOGLIPTINA) Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-66670886
Email: info@dakenchem.com
Products Intro: Product Name:ALOGLIPTIN(ALOGLIPTINE, ALOGLIPTINA)
CAS:850649-61-5
Purity:99% Package:100g,500g,1kg,5kg,10kg
Company Name: Beijing Cooperate Pharmaceutical Co.,Ltd
Tel: 010-60279497
Email: sales01@cooperate-pharm.com
Products Intro: Product Name:Alogliptin
CAS:850649-61-5
Purity:98% Package:100G;1KG;5KG;10KG;25KG;50KG;100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: CAS:850649-61-5
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Shanghai Yingrui Biopharma Co., Ltd.
Tel: +86-21-33585366 E-mail:sales03@shyrchem.com
Email: sales03@shyrchem.com
Products Intro: Product Name:Alogliptin
CAS:850649-61-5
Purity:99% Package:100g;500g;1kg;25kg...
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +86 21 5161 9050/ 5187 7795
Email: ivan@atkchemical.com
Products Intro: CAS:850649-61-5
Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G

Lastest Price from ALOGLIPTIN(ALOGLIPTINE, ALOGLIPTINA) manufacturers

  • Alogliptin
  • US $1070.00 / KG
  • 2021-09-26
  • CAS:850649-61-5
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 600KG
  • Alogliptin
  • US $15.00-10.00 / KG
  • 2021-07-13
  • CAS:850649-61-5
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
  • Alogliptin
  • US $15.00-10.00 / KG
  • 2021-07-10
  • CAS:850649-61-5
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
ALOGLIPTIN(ALOGLIPTINE, ALOGLIPTINA) Basic information
Product Name:ALOGLIPTIN(ALOGLIPTINE, ALOGLIPTINA)
Synonyms:Alogliptin (SYR-322);Alogliptin(free base);Benzonitrile, 2-[[6-[(3R)-3-aMino-1-piperidinyl]-3,4-dihydro-3-Methyl-2,4-dioxo-1(2H)-pyriMidinyl]Methyl]-;Axagliptin hydrate;(R)-2-[6-(3-aMino-piperidin-1-yl)-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl]-benzonitrile;Alogliptin Benzoate API;Alogliptin 2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile;Trajenta
CAS:850649-61-5
MF:C18H21N5O2
MW:339.39
EINECS:821-899-3
Product Categories:Inhibitor;Intermediates & Fine Chemicals;Amines;Pharmaceuticals;intermediat;Inhibitors;Aromatics;Chiral Reagents;Heterocycles
Mol File:850649-61-5.mol
ALOGLIPTIN(ALOGLIPTINE, ALOGLIPTINA) Structure
ALOGLIPTIN(ALOGLIPTINE, ALOGLIPTINA) Chemical Properties
Boiling point 519.2±60.0 °C(Predicted)
density 1.342
Fp 267.8℃
pka9.89±0.20(Predicted)
Safety Information
Safety Statements 24/25
RIDADR 3077
HS Code 29335990
Hazardous Substances Data850649-61-5(Hazardous Substances Data)
MSDS Information
ALOGLIPTIN(ALOGLIPTINE, ALOGLIPTINA) Usage And Synthesis
DescriptionAlogliptin is a dipeptidyl-peptidase IV (DPP-4) inhibitor that was approved in Japan in 2010 for treatment of type 2 diabetes, a disease in which insulin resistance and β-cell dysfunction lead to hyperglycemia. As islet function is lost, the severity of insulin resistance increases. The introduction of DPP-4 inhibitors has brought a novel class of insulinotropic agents for the treatment options available to type 2 diabetic patients. The therapeutic potential of glucagon-like peptide 1 (GLP-1), an incretin peptide, for the treatment of type 2 diabetes was realized in the 1990s. The insulinotropic effects of GLP-1 depend closely on glucose concentrations providing the possibility of glucose normalization without the risk of hypoglycemia. GLP-1 has other non-insulinotropic physiological actions that are advantageous. It suppresses glucagon secretion from a cells and slows gastric emptying, which contributes to satiety and to a slower passage and reabsorption of carbohydrates. GLP-1 also contributes to satiety via a central mechanism as a neurotransmitter with effects on the hypothalamus.
Chemical PropertiesWhite Solid
OriginatorSyrrx Inc. (now Takeda San Diego) (Japan)
UsesAlogliptin is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Antidiabetic agent.
DefinitionChEBI: A piperidine that is 3-methyl-2,4-dioxo-3,4-dihydropyrimidine carrying additional 2-cyanobenzyl and 3-aminopiperidin-1-yl groups at positions 1 and 2 respectively (the R-enantiomer). Used in the form of its benzoate salt for treatment of t pe 2 diabetes.
Brand nameNesina
ALOGLIPTIN(ALOGLIPTINE, ALOGLIPTINA) Preparation Products And Raw materials
Tag:ALOGLIPTIN(ALOGLIPTINE, ALOGLIPTINA)(850649-61-5) Related Product Information
Alogliptin Related Compound 26 Benzonitrile, 2-[(tetrahydro-3-Methyl-2,4,6-trioxo-1(2H)-pyriMidinyl)Methyl]- 2,4(1H,3H)-Pyrimidinedione, 6-methoxy-3-methyl- (S)-Alogliptin Benzoate Salt Alogliptin iMpurity AGOMELATINE Linagliptin Alogliptin benzoate Trelagliptin TAK-438 Trelagliptin succinate Teneligliptin Tozasertib Telmisartan Atazanavir sulfate Erteberel (LY500307) Rapamycin Olaparib