| Company Name: |
MQ (shanghai) Pharmaceuticals Co., Ltd.
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| Tel: |
13761635123 |
| Email: |
1014988033@qq.com |
| Products Intro: |
Product Name:N-((1R,2R)-2-(4-(2-Methoxyphenyl)piperazin-1-yl)cyclohexyl)benzenesulfonamide
CAS:2418594-00-8
Purity:＞95% Package:1G，5G
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| Company Name: |
Bide Pharmatech Ltd.
|
| Tel: |
400-1647117 15221909166 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:N-((1R,2R)-2-(4-(2-Methoxyphenyl)piperazin-1-yl)cyclohexyl)benzenesulfonamide
CAS:2418594-00-8
Purity:98% Package:5mg;10mg;25mg; Remarks:BD01505390
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| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:(1R,2R)-ML-SI3
CAS:2418594-00-8
Purity:98% Package:100 mg；50 mg
|
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| | Benzenesulfonamide, N-[(1R,2R)-2-[4-(2-methoxyphenyl)-1-piperazinyl]cyclohexyl]- Basic information |
| | Benzenesulfonamide, N-[(1R,2R)-2-[4-(2-methoxyphenyl)-1-piperazinyl]cyclohexyl]- Chemical Properties |
| Boiling point | 589.3±60.0 °C(Predicted) | | density | 1.26±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 11.63±0.40(Predicted) |
| | Benzenesulfonamide, N-[(1R,2R)-2-[4-(2-methoxyphenyl)-1-piperazinyl]cyclohexyl]- Usage And Synthesis |
| Biological Activity | (1R,2R)-ML-SI3 is a potent inhibitor of both TRPML1 and TRPML2 (IC50 values of 1.6 and 2.3 μM) and a weak inhibitor (IC50 12.5 μM) of TRPML3[1]. | | References | [1]. Leser C, Keller M, Gerndt S, et al. Chemical and pharmacological characterization of the TRPML calcium channel blockers ML-SI1 and ML-SI3. Eur J Med Chem. 2021;210:112966. |
| | Benzenesulfonamide, N-[(1R,2R)-2-[4-(2-methoxyphenyl)-1-piperazinyl]cyclohexyl]- Preparation Products And Raw materials |
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