- Laurolitsine
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- $0.00 / 20mg
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2023-02-24
- CAS:5890-18-6
- Min. Order: 20mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- LAUROLITSINE
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- $1.00 / 1g
-
2019-12-23
- CAS:5890-18-6
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 1000KGS
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| | LAUROLITSINE Basic information |
| Product Name: | LAUROLITSINE | | Synonyms: | (6aS)-5,6,6a,7-Tetrahydro-1,10-dimethoxy-4H-dibenzo[de,g]quinoline-2,9-diol;(S)-5,6,6a,7-Tetrahydro-1,10-dimethoxy-4H-dibenzo[de,g]quinoline-2,9-diol;1,10-Dimethoxy-6aα-noraporphine-2,9-diol;Norboldine;4H-Dibenzo[de,G]quinoline-2,9-diol, 5,6,6A,7-tetrahydro-1,10-dimethoxy-, (6as)-;Aids161652;Aids-161652;Laurolistine | | CAS: | 5890-18-6 | | MF: | C18H19NO4 | | MW: | 313.35 | | EINECS: | | | Product Categories: | Alkaloids | | Mol File: | 5890-18-6.mol |  |
| | LAUROLITSINE Chemical Properties |
| Melting point | 138-140 ºC | | Boiling point | 453.15°C (rough estimate) | | density | 1.313 | | refractive index | 1.5100 (estimate) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Cryst. | | pka | 9.81±0.20(Predicted) |
| | LAUROLITSINE Usage And Synthesis |
| Description | This noraporphiae alkaloid has been obtained from Litsea japonica and Neolitsea
sericea and swells at 11 5-8°C before melting. It is dextrorotatory with [o:lbl +
102.5° (EtOH) and yields a picrate as yellow needles, m.p. 212°C (dec.) and a
picrolonate, m.p. 239°C (dec.). The N-methyl derivative is identical with boldine. | | Uses | Laurolitsine is an alkaloid extracted from Polyalthia longifolia var. pendula. | | Definition | ChEBI: An isoquinoline alkaloid that is noraporphine substituted by hydroxy groups at positions 2 and 9 and methoxy groups at positions 1 and 10. Isolated from Litsea glutinosa and Lindera chunii, exhibits inhibitory activity against HIV
1 integrase. | | References | Nakasato, Nomura., Chem. Pharm. Bull., (Tokyo), 7, 780 (1959)
Kozuka., J. Ph arm. Soc., Japan, 82, 1567 (1962)
See also:
Johns, Lamberton., Austral. J. Chem., 20, 1277 (1967) |
| | LAUROLITSINE Preparation Products And Raw materials |
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