阿珠莫林
中文名称 | 阿珠莫林 |
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中文同义词 | 阿珠莫林 |
英文名称 | Azumolene |
英文同义词 | Azumolene;1-[[[5-(4-Bromophenyl)-2-oxazolyl]methylene]amino]hydantoin;2,4-Imidazolidinedione, 1-[[[5-(4-bromophenyl)-2-oxazolyl]methylene]amino]-;EU4093 free base;SOCE,inhibit,Azumolene,EU-4093,ryanodine,Inhibitor,Ca channels,EU 4093,Calcium Channel,relaxant,Ca2+ channels,muscle,EU4093,receptor,calcium |
CAS号 | 64748-79-4 |
分子式 | C13H9BrN4O3 |
分子量 | 349.14 |
EINECS号 | |
相关类别 | |
Mol文件 | 64748-79-4.mol |
结构式 |
阿珠莫林 性质
储存条件 | Store at -20°C |
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溶解度 | 二甲基亚砜:13.89 mg/mL(39.78 mM) |
形态 | 固体 |
颜色 | 白色至浅棕色 |
Pretreatment with 20 µM Azumolene for 1-2 min inhibits SOCE activated by subsequent addition of caffeine and ryanodine to promote RyR-dependent sarcoplasmic reticulum Ca 2+ store depletion in mouse myotubes and adult muscle fibers.
The effect of Azumolene (EU4093) on the twitch of the intact rat soleus preparation is nearly maximal at a dose of 20 mg/kg. This dose of Azumolene reduces the amplitude of the twitch to 31.9% of the control value. The contraction of intrafusal muscle as measured by the response of spindle afferent discharge is also reduced by Azumolene.
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/08/19 | HY-113920A | Azumolene | 1 mg | 384元 | |
2024/08/19 | HY-113920A | 阿珠莫林 Azumolene | 64748-79-4 | 5mg | 960元 |