4-Oxazoleacetic acid, 2-(4-chlorophenyl)-5-(2-furanyl)-, ethyl ester
| 中文名称 | 4-Oxazoleacetic acid, 2-(4-chlorophenyl)-5-(2-furanyl)-, ethyl ester |
|---|---|
| 中文同义词 | 化合物 T13909;化合物 TA-1801 |
| 英文名称 | 4-Oxazoleacetic acid, 2-(4-chlorophenyl)-5-(2-furanyl)-, ethyl ester |
| 英文同义词 | 4-Oxazoleacetic acid, 2-(4-chlorophenyl)-5-(2-furanyl)-, ethyl ester;ethyl 2-(4-chlorophenyl)-5-(2-furyl)-4-oxzoleacetate;TA-1801;TA1801,TA 1801;Ethyl 2-(4-chlorophenyl)-5-(2-furyl)oxazole-4-acetate |
| CAS号 | 88352-44-7 |
| 分子式 | C17H14ClNO4 |
| 分子量 | 331.75 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 88352-44-7.mol |
| 结构式 |  |
4-Oxazoleacetic acid, 2-(4-chlorophenyl)-5-(2-furanyl)-, ethyl ester 性质
| 熔点 | 107-108 °C(Solv: ethanol (64-17-5)) |
|---|---|
| 沸点 | 471.0±55.0 °C(Predicted) |
| 密度 | 1.275±0.06 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | -1.21±0.26(Predicted) |
TA-1801 是一种降血脂剂。
TA-1801 inhibits platelet aggregation in vitro.
TA-1801 reduces serum cholesterol and triglyceride levels by 23% and 35%, respectively, at a dose of 0.05% in a diet in normal rats, and it is about 10 times more active in hereditary hyperlipidemic rats (THLR/1) than in normal rats.