人参皂苷RG6
| 中文名称 | 人参皂苷RG6 |
|---|---|
| 中文同义词 | 人参皂苷RG6;人参皂苷RG6对照品,;人参皂苷, 来源于人参;人参皂甙 RB6 |
| 英文名称 | Ginsenoside Rg6 |
| 英文同义词 | Ginsenoside Rg6;daMMar-20(21),24-diene-3β,6α,12β-trihydroxy-6-O-α-L-rhaMnopyranosyl(-1→2)-β-D-glucopyranoside;(3beta,6alpha,12beta)-3,12-Dihydroxydammara-20,24-dien-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside;Ginsenoside Rg6, 98%, from Panax ginseng C. A. Mey.;b-D-Glucopyranoside, (3b,6a,12b)-3,12-dihydroxydammara-20,24-dien-6-yl 2-O-(6-deoxy-a-L-mannopyranosyl)-;β-D-Glucopyranoside, (3β,6α,12β)-3,12-dihydroxydammara-20,24-dien-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-;Ginsenoside Rg6 USP/EP/BP |
| CAS号 | 147419-93-0 |
| 分子式 | C42H70O12 |
| 分子量 | 767 |
| EINECS号 | |
| 植物来源 | 人参 |
| 相关类别 | 对照品;中药对照品;植物提取物;皂苷;标准品;分析试剂标准品;对照品-中药对照品;标准品 -中药标准品;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Triterpenoids;标准品-对照品;标准品，对照品 |
| Mol文件 | 147419-93-0.mol |
| 结构式 |  |
人参皂苷RG6 性质
| 沸点 | 850.6±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.27±0.1 g/cm3(Predicted) |
| 储存条件 | 2-8°C |
| 溶解度 | 溶于氯仿、二氯甲烷、乙酸乙酯、DMSO、丙酮等。 |
| 形态 | 粉末 |
| 酸度系数(pKa) | 12.85±0.70(Predicted) |
|
NF-κB 25.12 μM (IC 50 , in SK-Hep1 cell) |
NF-κB 29.34 μM (IC 50 , in HepG2 cell) |
Apoptosis
|
Ginsenoside Rg6 inhibits TNF-α-induced NF-κB transcriptional activity with an IC 50 of 25.12±1.04 μM in SK-Hep1 cells, consistent with the data from HepG2 cells. Ginsenoside Rg6 exhibits obvious anti-proliferative and apoptosis-inducing effects when it is applied to JK cells in vitro. Ginsenoside Rg6 blocks S arrest in the cell cycle. CCK-8 method shows that after Ginsenoside Rg6 is used, several groups with different concentrations obviously inhibits JK cell proliferation in human lymphocytoma, with evident dose dependency. Based on IC 50 , the median inhibitory concentration of Ginsenoside Rg6 is 83.08 μM.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-N0907 | 人参皂苷RG6 Ginsenoside Rg6 | 147419-93-0 | 1mg | 1350元 |
| 2024/01/25 | HY-N0907 | 人参皂苷RG6 Ginsenoside Rg6 | 147419-93-0 | 5mg | 3400元 |