- 2'-O-Methylcytidine
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- $6.00 / 1KG
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2024-03-29
- CAS:2140-72-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- 2'-O-Methylcytidine
-
- $0.00 / 1KG
-
2024-02-06
- CAS:2140-72-9
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 300KG per month
- 2'-O-Methylcytidine
-
- $0.00 / 1kg
-
2023-04-04
- CAS:2140-72-9
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 500kg per month
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| | 2'-O-Methylcytidine Basic information |
| Product Name: | 2'-O-Methylcytidine | | Synonyms: | 2'-OMe-C;4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]pyrimidin-2-one;4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one;4-azanyl-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]pyrimidin-2-one;2'-OMe Cytidine;4-aMino-1-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)-3-Methoxyoxolan-2-yl]-1,2-dihydropyriMidin-2-one;2'-O-Methylcytidine, >=99%;2'-O-METHYLCYTIDINE | | CAS: | 2140-72-9 | | MF: | C10H15N3O5 | | MW: | 257.24 | | EINECS: | 2017-001-1 | | Product Categories: | Bases & Related Reagents;Carbohydrates & Derivatives;Heterocycles;Nucleotides;Nucleosides, Nucleotides, Oligonucleotides;Biochemicals and Reagents;Nucleoside Analogs;Nucleosides;Modified（deoxy）nucleoside | | Mol File: | 2140-72-9.mol |  |
| | 2'-O-Methylcytidine Chemical Properties |
| Melting point | 252-253 C | | Boiling point | 506.0±60.0 °C(Predicted) | | density | 1.68±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C | | solubility | Soluble in DMSO. | | pka | 13.37±0.70(Predicted) | | form | Powder | | color | White to Off-white | | InChI | InChI=1S/C10H15N3O5/c1-17-8-7(15)5(4-14)18-9(8)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1 | | InChIKey | RFCQJGFZUQFYRF-ZOQUXTDFSA-N | | SMILES | OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](OC)[C@@H]1O | | CAS DataBase Reference | 2140-72-9(CAS DataBase Reference) |
| | 2'-O-Methylcytidine Usage And Synthesis |
| Description | 2'-O-Methylcytidine is a nucleoside with a hydroxyl group on the 2' carbon, making it an effective viral replication inhibitor. 2'-O-Methylcytidine is also metabolized by nucleotide salvage pathways and may be able to bind to the response element on DNA, which could inhibit protein synthesis in cancer cells. It is an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50 = 3.8 μM). It inhibits HCV replication in a replicon assay (IC50 = 21.2 μM). | | Chemical Properties | White powder | | Uses | Cytidine analog. | | Uses | 2'-O-Methylcytidine is used in the preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase. | | Definition | ChEBI: 2'-O-methylcytidine is a methylcytidine. |
| | 2'-O-Methylcytidine Preparation Products And Raw materials |
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