207277-66-5
| 中文名称 | 207277-66-5 |
|---|---|
| 中文同义词 | 化合物 T12239 |
| 英文名称 | NNC45-0781 |
| 英文同义词 | NNC45-0781;2H-1-Benzopyran-7-ol, 3,4-dihydro-3-phenyl-4-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-, (3S,4R)-;NNC45 0781,NNC-45-0781,NNC450781 |
| CAS号 | 207277-66-5 |
| 分子式 | C27H29NO3 |
| 分子量 | 415.52 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 207277-66-5.mol |
| 结构式 |  |
207277-66-5 性质
| 沸点 | 563.7±50.0 °C(Predicted) |
|---|---|
| 密度 | 1.185±0.06 g/cm3(Predicted) |
| 酸度系数(pKa) | 9.87±0.60(Predicted) |
NNC45-0781 是一种组织选择性的雌激素 (estrogen) 部分激动剂。
Estrogen Receptor
NNC45-0781 (NNC 45-0781) shows that it is a very promising tissue-selective estrogen agonist. Total serum cholesterol is significantly increased in the vehicle-treated group as compared to the sham animals. All of the animals receiving NNC45-0781 at doses of 10 nmol/g or higher, has significantly lower levels of total serum cholesterol as compared to the vehicle treated group.