中文名称 | (S)-norcolaurine |
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中文同义词 | |
英文名称 | (S)-norcolaurine |
英文同义词 | (S)-norcolaurine;(S)-Higenamine;6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-, (1S)- |
CAS号 | 22672-77-1 |
分子式 | C16H17NO3 |
分子量 | 271.31 |
EINECS号 | |
相关类别 | |
Mol文件 | 22672-77-1.mol |
结构式 |
(S)-norcolaurine 性质
熔点 | 255-256 °C |
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沸点 | 522.4±50.0 °C(Predicted) |
密度 | 1.317±0.06 g/cm3(Predicted) |
酸度系数(pKa) | 9.72±0.40(Predicted) |
(S)-Higenamine ((S)-Norcoclaurine),Higenamine 的 S 型异构体,是苄基异喹啉生物碱生物合成的起始化合物,由去甲月桂碱合酶 (NCS) 将多巴胺和 4-羟基苯乙醛 (4-HPAA) 缩合生成。
The biosynthetic pathway leading to benzylisoquinoline alkaloids originates from the enzyme-catalyzed condensation of dopamine and 4-hydrophenylacetaldehyde to yield (S)-norcoclaurine. Both substrates are secondary metabolites derived from the decarboxylation/hydroxylation/deamination of tyrosine.