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α-Ethyltryptamine

α-Ethyltryptamine Basic information
Product Name:α-Ethyltryptamine
Synonyms:AURORA KA-7710;1-(1H-INDOL-3-YLMETHYL)-PROPYLAMINE;3-(2-AMINOBUTYL)INDOLE;ALPHA-ETHYLTRYPTAMINE;3-(2-Aminobutyl)-1H-indole;α-Ethyl-1H-indole-3-ethan-1-amine;α-Ethyltryptamine;1H-Indole-3-ethanamine, .alpha.-ethyl-
CAS:2235-90-7
MF:C12H16N2
MW:188.27
EINECS:
Product Categories:Amines, Drug Analogues, Indole Derivatives, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:2235-90-7.mol
α-Ethyltryptamine Structure
α-Ethyltryptamine Chemical Properties
Melting point 97-99°
Boiling point 313.29°C (rough estimate)
density 0.9520 (rough estimate)
refractive index 1.5600 (estimate)
solubility DMF: 11 mg/ml; DMSO: 5 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form A crystalline solid
pka17.22±0.30(Predicted)
Water Solubility 0.51g/L(room temperature)
Safety Information
MSDS Information
α-Ethyltryptamine Usage And Synthesis
OriginatorMonase,Upjohn,US,1961
Usesα-Ethyltryptamine (E931900) is used as a stimulant and entactogen that have actions at multiple central nervous system (CNS) receptor sites.
DefinitionChEBI: Etryptamine is a member of indoles.
Manufacturing ProcessA mixture of 5 parts of 3-(2'-ethyl-2'-nitrovinyl)indole in 80 parts of ethanol saturated with ammonia gas is shaken in an atmosphere of hydrogen at 100 atmospheres pressure and at 20°C in the presence of 1 part of a 5%
palladium on carbon catalyst until the theoretical amount of hydrogen is absorbed. The catalyst is removed by filtration. The ethanol and ammonia are then removed from the filtrate by distillation under reduced pressure. The residual oil is dissolved in 170 parts of dry ether, 50 parts of potassium hydroxide pellets are added and the solution is kept at 18°C to 22°C for 2 hours. The mixture is filtered and hydrogen chloride is passed into the filtrate to precipitate crude (α-ethyltryptamine hydrochloride. This is purified by crystallization from methanol/ethyl acetate and it then has a MP of 221°C.
Therapeutic FunctionCentral stimulant
α-Ethyltryptamine Preparation Products And Raw materials
Raw materialsHydrogen
Tag:α-Ethyltryptamine(2235-90-7) Related Product Information
S-(-)-LISURIDE Dihydroergotoxine mesylate α-Ethyltryptamine DIHYDROERGOTAMINE MESYLATE Pergolide mesylate salt AGROCLAVINE METERGOLINE DIHYDROERGOCRISTINE MESYLATE DIHYDROERGOTAMINE TARTRATE S(+)-N,N-DIETHYL-N'([8ALPHA]-6-METHYLERGOLIN-8-YL)UREA Tryptamine etryptamine acetate CYCLOPIAZONIC ACID Dihydro α-Ergocryptine CHAETOGLOBOSINC 9,10-Dihydrolysergol SARPAGINE spegatrine