PYR-HIS-TRP-SER-TYR-D-LYS-LEU-ARG-PRO-GLY-NH2

PYR-HIS-TRP-SER-TYR-D-LYS-LEU-ARG-PRO-GLY-NH2 Suppliers list
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Products Intro: Product Name:PYR-HIS-TRP-SER-TYR-D-LYS-LEU-ARG-PRO-GLY-NH2
CAS:52671-12-2
Purity:98% Package:10Mg;100Mg;1g;5g
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Products Intro: Product Name:Glp-His-Trp-Ser-Tyr-DLys-Leu-Arg-Pro-Gly-NH2
CAS:52671-12-2
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Products Intro: Product Name:Glp-His-Trp-Ser-Tyr-DLys-Leu-Arg-Pro-Gly-NH2
CAS:52671-12-2
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Products Intro: Product Name:[D-Lys6]-LH-RH
CAS:52671-12-2
Purity:98% Package:10mg;100mg;1000mg
PYR-HIS-TRP-SER-TYR-D-LYS-LEU-ARG-PRO-GLY-NH2 Basic information
Product Name:PYR-HIS-TRP-SER-TYR-D-LYS-LEU-ARG-PRO-GLY-NH2
Synonyms:lys(6)-lhr;PYROGLU-HIS-TRP-SER-TYR-D-LYS-LEU-ARG-PRO-GLY NH2;PGLU-HIS-TRP-SER-TYR-D-LYS-LEU-ARG-PRO-GLY-NH2;GLP-HIS-TRP-SER-TYR-D-LYS-LEU-ARG-PRO-GLY-NH2;(D-LYS6)-GONADOTROPIN-RELEASING HORMONE;[D-LYS6]-LH-RH (HUMAN);(D-LYS6)-LUTEINIZING HORMONE-RELEASING FACTOR;(D-LYS6)-LUTEINIZING HORMONE-RELEASING HORMONE
CAS:52671-12-2
MF:C59H84N18O13
MW:1253.41
EINECS:
Product Categories:Gonadotropin-releasing hormone (GnRH);Androgen ModulatorsNeuropeptides;LH-RHCancer Research;Antitumor Agents;Cancer Research;LH-RHPeptides for Cell Biology;Releasing Factors;Therapy Adjuncts;Tumor Growth Regulation
Mol File:52671-12-2.mol
PYR-HIS-TRP-SER-TYR-D-LYS-LEU-ARG-PRO-GLY-NH2 Structure
PYR-HIS-TRP-SER-TYR-D-LYS-LEU-ARG-PRO-GLY-NH2 Chemical Properties
density 1.51±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
storage temp. −20°C
form powder
pka9.82±0.15(predicted)
Sequence{Glp}-His-Trp-Ser-Tyr-{d-Lys}-Leu-Arg-Pro-Gly-NH2
Safety Information
Hazard Codes T
Risk Statements 60
Safety Statements 53-22-36/37/39-45
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
PYR-HIS-TRP-SER-TYR-D-LYS-LEU-ARG-PRO-GLY-NH2 Usage And Synthesis
Uses[D-Lys6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Lys6]-LH-RH acts as a GnRH receptor agonist[1].
in vivo

[D-Lys6]-LH-RH (100?μg, minipumps implanted subcutaneously) inhibits tumor growth in Dunning R-3327H prostate cancer rats[1].

Animal Model:Dunning R-3327H prostate cancer rats[1]
Dosage:100?μg
Administration:Alzet minipumps implanted subcutaneously
Result:Inhibited tumor growth compared with control.
References[1] Pinski J, et al. Inhibition of growth of experimental prostate cancer in rats by LH-RH analogs linked to cytotoxic radicals. Prostate. 1993;23(2):165-78. DOI:10.1002/pros.2990230209
PYR-HIS-TRP-SER-TYR-D-LYS-LEU-ARG-PRO-GLY-NH2 Preparation Products And Raw materials
Tag:PYR-HIS-TRP-SER-TYR-D-LYS-LEU-ARG-PRO-GLY-NH2(52671-12-2) Related Product Information

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