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| | carbamoyl chloride Basic information |
| Product Name: | carbamoyl chloride | | Synonyms: | chloroformamide;Carbaminoyl chloride;Urea chloride;carbamoyl chloride;N-chloro-N-methylformamide;Carbamic chloride (9CI);N-Carbamic chloride;carbamic chloride | | CAS: | 463-72-9 | | MF: | CH2ClNO | | MW: | 79.49 | | EINECS: | 207-342-1 | | Product Categories: | | | Mol File: | 463-72-9.mol |  |
| | carbamoyl chloride Chemical Properties |
| Melting point | 90℃ | | Boiling point | bp 61-62° (decompn) | | density | 1.3273 (rough estimate) | | refractive index | 1.4480 (estimate) | | pka | 11.60±0.50(Predicted) |
| | carbamoyl chloride Usage And Synthesis |
| Chemical Properties | Carbamoyl chloride,
H2N – COCl, is unstable; it may be stabilized by Lewis acids (e.g., aluminum chloride) as adducts
and in this form can be used in the Friedel-Crafts
acylation of arenes. Since many of the
monosubstituted carbamoyl chlorides also deteriorate on storage, the corresponding isocyanates
are used instead. Disubstituted carbamoyl chlorides are stable and can be stored for prolonged
periods. | | Physical properties | The simple carbamoyl
chlorides are colorless liquids or solids, usually
with pungent odor. | | Uses | Carbamoyl chloride can be used as an intermediate for carbamate pesticides. | | Uses | Carbamoyl chlorides are intermediates with many uses. Of primary industrial
importance are the reactions with alcohols, phenols, and oximes to give carbamic acid esters;
with thiols (mercaptans) to give thiocarbamates;
with amines and hydroxylamines to give substituted ureas; and with imidazoles and triazoles to
give carbamoyl azoles. | | Definition | ChEBI: Carbamyl chloride is an organonitrogen compound. | | Synthesis | Carbamoyl chloride can be synthesized from methylamine and phosgene at 200-240℃.
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| | carbamoyl chloride Preparation Products And Raw materials |
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