Tris(hydroxymethyl)aminoethane 77-86-1 Trometamol

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Tris(hydroxymethyl)aminoethane CAS 77-86-1

Trometamol CAS 77-86-1

Tris(hydroxymethyl)aminoethane CAS 77-86-1

Tris(hydroxymethyl)aminomethane; 2-Amino-2-(hydroxymethyl)-1,3-propanediol; Tromethamine; Tromethane; THAM CAS 77-86-1

Name:    Tris Base
Synonyms:    2-amino-2-(hydroxymethyl)-3-propanediol;2-Amino-2-hydroxymethylpropanediol;2-Amino-2-methylol-1,3-propanediol;3-Propanediol,2-amino-2-(hydroxymethyl)-1;Addex-Tham;Amino-2-(hydroxymethyl)-1,3-propanediol;Aminotrimethylolmethane;Aminotris(hydroxymethyl)methane
CAS:    77-86-1
MF:    C4H11NO3
MW:    121.14
EINECS:    201-064-4
Product Categories:    Biochemistry;Reagents for Electrophoresis;Buffer;ACS Grade Buffers;Amino Alcohols;Biological Buffers;-;Buffers A to Z;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;API;Pharmaceutical intermediates;#N/A
Mol File:    77-86-1.mol
Tris Base Structure
 Tris or Tris(hydroxymethyl)aminomethane or THAM is an organic compound with the formula (HOCH2)3CNH2. Tris is extensively used in biochemistry and molecular biology. In biochemistry, Tris is widely used as a component of buffer solutions, such as in TAE and TBE buffer, especially for solutions of nucleic acids. It contains a primary amine and thus undergoes the reactions associated with typical amines, e.g. condensations with aldehydes.
 TRIS; Pehanorm; THAM; 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-; 8VTE 1L; Expand
CAS No.     77-86-1
Molecular Formula     C4H11NO3
Molecular Weight     121.13500
PSA     86.71000
LogP     -1.63890
Properties
Appearance & Physical State     white crystalline powder
Density     1.353
Boiling Point     219-220ºC (10 mmHg)
Melting Point     167-172ºC
Flash Point     100ºC
Refractive Index     1.531
Water Solubility     550 g/L (25 ºC)
Stability     Stable. Incompatible with bases, strong oxidizing agents. Protect from moisture.
Storage Condition     2-8ºC
Safety Info
RTECS     TY2900000
Safety Statements     S26-S37/39
HS Code     29221980
2-Amino-2-hydroxymethyl-1,3-propanediol; TRIS; Tromethamine; Tromethane; tris(hydroxyme.)aminomethane; trizma base; Trometamol; tri(hydroxymethyl)methylamine; Tris(hydroxymethyl) methylamine Tris buffer 99.8+ %; Trihydroxymethyl Aminomethane; Tris, Ultra Pure; Tris, Tissue Culture Tested Tris(hydroxymethyl)aminomethane, Tissue Culture Tested; Tris, Alcohol Free Tris(hydroxymethyl)aminomethane, Alcohol Free; Tris(hydroxymethyl)aminomethane, Ultra Pure, Molecular Biology Grade; Tris EDTA acetate buffer; THAM; Trimethanolaminomethane; Tri(hydroxymethyl)aminomethane; Tris(hydroxymethyl)aminomethane; 2-Amino-2-(hydroxymethyl)-1,3-propanediol; Tris hydroxyl methyl amino methane; 2-amino-2-(hydroxymethyl)propane-1,3-diol; 1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium; (methylamino)methanetriol; Tris(hydroxymethyl) aminomethane; Tris(hydroxymethyl)amino methane; Tris Base
CAS RN.:     
77-86-1
EINECS:     201-064-4
Tris Base Chemical Properties
Melting point     167-172 °C(lit.)
Boiling point     219-220 °C10 mm Hg(lit.)
density     1,353 g/cm3
vapor pressure     0.0267 hPa (20 °C)
refractive index     1.4170 (estimate)
Fp     219-220°C/10mm
storage temp.     2-8°C
solubility     H2O: 4 M at 20 °C, clear, colorless
form     crystalline
color     white
PH    10.5-12.0(4 m in water, 25 °C)
pka    8.1(at 25℃)
PH Range    7 - 9
Water Solubility     550 g/L (25 ºC)
Sensitive     Hygroscopic
λmax    λ: 260 nm Amax: 0.10
λ: 280 nm Amax: 0.08
Merck     14,9772
BRN     741883
Stability:    Stable. Incompatible with bases, strong oxidizing agents. Protect from moisture.
InChIKey    LENZDBCJOHFCAS-UHFFFAOYSA-N
CAS DataBase Reference    77-86-1(CAS DataBase Reference)
NIST Chemistry Reference    1,3-Propanediol, 2-amino-2-(hydroxymethyl)-(77-86-1)
EPA Substance Registry System    1,3-Propanediol, 2-amino-2-(hydroxymethyl)- (77-86-1)
Safety Information
Hazard Codes     Xi
Risk Statements     36/37/38
Safety Statements     26-36-37/39-24/25-23
WGK Germany     2
RTECS     TY2900000
F     3
TSCA     Yes
HazardClass     IRRITANT
HS Code     29221980