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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Neuronal Signaling>Histamine Receptor Antagonists>Olopatadine Hydrochloride
Olopatadine Hydrochloride
  • Olopatadine Hydrochloride
  • Olopatadine Hydrochloride
  • Olopatadine Hydrochloride
  • Olopatadine Hydrochloride
  • Olopatadine Hydrochloride

Olopatadine Hydrochloride

Price $80
Package 10g
Min. Order: 10g
Supply Ability: 10tons
Update Time: 2021-03-17

Product Details

Product Name: Olopatadine Hydrochloride CAS No.: 140462-76-6
Min. Order: 10g Purity: 99.8%
Supply Ability: 10tons Release date: 2021/03/17

Olopatadine Hydrochloride

Use of Olopatadine Hydrochloride


Olopatadine HCl is a histamine blocker used to treat allergic conjunctivitis.Target: Histamine ReceptorOlopatadine is one of the second-generation histamine H1 receptor antagonists that are treated for allergic disorders. Olopatadine significantly inhibited the ear swelling and the increased production of IL-4, IL-1beta, IL-6, GM-CSF and NGF in the lesioned ear [1]. Olopatadine was highly and rapidly absorbed in healthy human volunteers. The urinary excretion of olopatadine accounted for not less than 58% and the contribution of metabolism was considerably low in the clearance of olopatadine in humans. Olopatadine is one of the few renal clearance drugs in antiallergic drugs. Olopatadine was shown to be useful for the treatment of allergic rhinitis and chronic urticaria in double-blind clinical trials [2]. AL-4943A inhibits histamine release in a concentration-dependent fashion (IC50 = 559 microM) from human conjunctival mast cell preparations in vitro. Passive anaphylaxis in guinea pig conjunctiva was attenuated by AL-4943A applied 30 min prior to intravenous or topical ocular antigen challenge (ED50 values 0.0067% and 0.0170%, w/v, respectively) [3].

Common Name
Olopatadine Hydrochloride
CAS Number
140462-76-6
Molecular Weight
373.873
Density
1.221 g/cm3
Boiling Point
523ºC at 760mmHg
Molecular Formula
C21H24ClNO3
Melting Point
242-245ºC

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Article illustration

 

Company Profile Introduction

Welcome to hebei Shuoxi biotechnology co., LTD. Shuoxi is a fast developing pharmaceutical intermediates enterprise located in shijiazhuang, capital of hebei province. Shuoxi analysis research and development center also provides custom synthesis service. Hebei Shuoxi biotechnology co., LTD can provide customized synthetic chemicals in different quantities in laboratories, factories and industrial scale. We have more than 10 years experience in this field. We can offer competitive price for every customer and guarantee the quality of our products. 3. We pay attention to the needs of each customer and build a good relationship with them. 4. We have long-term business relations with Canada, Mexico, Brazil, UK, Russia, Germany, USA, India, South Africa, Malta, Egypt, Armenia, Australia, Philippines, Belgium, Netherlands, Denmark and other countries. If you have any other questions for me. Please feel free to contact me. We only produce and sell products that are legal in China. All products are sold only to laboratory research.

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  • Since: 2016-11-14
  • Address: NO.108 ZHONGSHAN ROAD, QIAOXI DISTRICT, ShiJiazhuang CITY, CHINA
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