Afegostat D-Tartrate NEW
| Price | $390 | $987 | $1920 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-21 |
Product Details
| Product Name: Afegostat D-Tartrate | CAS No.: 957230-65-8 |
| Supply Ability: 10g | Release date: 2025/08/21 |
Product Introduction
Bioactivity
| Name | Afegostat D-Tartrate |
| Description | Afegostat D-Tartrate is a pharmacological chaperone that binds specifically and reversibly with high affinity to acid-β-glucosidase (GCase) in the endoplasmic reticulum. |
| In vivo | Afegostat D-Tartrate enhances GCase activity in the brain, liver, and spleen. When administered orally at a dosage of 100 mg/kg to Thy1-aSyn mice for four months, Afegostat notably improves motor and non-motor functions, eliminates microglial inflammatory responses in the substantia nigra, diminishes α-synuclein immunoreactivity in nigral dopaminergic neurons, and adjusts the size distribution of α-synuclein aggregates by reducing small aggregates and augmenting larger ones. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | GCase | Afegostat D-Tartrate | Afegostat DTartrate | Afegostat D Tartrate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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