ATG7-IN-3 NEW
| Price | $1460 | $1970 | $2660 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-05 |
Product Details
| Product Name: ATG7-IN-3 | CAS No.: 2226229-76-9 |
| Purity: 99.74% | Supply Ability: 10g |
| Release date: 2025/12/05 |
Product Introduction
Bioactivity
| Name | ATG7-IN-3 |
| Description | ATG7-IN-3 (Compound 18) is an effective ATG7 inhibitor (IC₅₀ = 48 nM) capable of suppressing autophagy, suitable for research into gliomas and colorectal cancers. |
| In vitro | ATG7-IN-3 exhibits inhibitory activity against ATG7 with an IC50 of 0.048 μM [1]. In glioma H4 cells, ATG7-IN-3 inhibits endogenous LC3B puncta formation with an IC50 of 0.938 μM [1]. In SKOV-3 cells, ATG7-IN-3 induces p62 accumulation with an EC50 value of 3.0 μM [1]. |
| In vivo | In the HCT-116 xenograft mouse model, ATG7-IN-3 (150 mg/kg, administered subcutaneously) modulates the autophagic markers LC3B and NBR1 [1]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80 mg/mL (212.53 mM), Sonication is recommended. |
| Inhibitors Related | Stavudine | Aceglutamide | Cysteamine hydrochloride | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Curcumin | Paeonol | Sodium butanoate | Naringin | Alginic acid | Gefitinib |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
Recommended supplier
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|---|---|---|---|---|
| $329.00/1mg |
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TargetMol Chemicals Inc.
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2025-12-05 | |
| $2500.00/100mg |
VIP4Y
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TargetMol Chemicals Inc.
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2025-10-27 | |
| $3.00/25KG |
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ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
|
2025-06-24 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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