BMS-199264 hydrochloride NEW
| Price | $939 | $1520 | $2430 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-10 |
Product Details
| Product Name: BMS-199264 hydrochloride | CAS No.: 186180-83-6 |
| Purity: 99.86% | Supply Ability: 10g |
| Release date: 2025/11/10 |
Product Introduction
Bioactivity
| Name | BMS-199264 hydrochloride |
| Description | BMS-199264 hydrochloride is the salt form of BMS-199264.BMS-199264 is a potent and selective inhibitor of mitochondrial F1F0 ATP hydrolase with an IC50=0.5 μM.BMS-199264 is able to inhibit the decline of ATP during myocardial ischemia, reduce myocardial necrosis, and enhance the recovery of myocardial contractile function after reperfusion. |
| In vitro | BMS-199264 hydrochloride selectively inhibits the hydrolase activity of mitochondrial F₁F₀ ATP synthase in vitro (IC₅₀ = 0.5 μM), without significant effects on its synthase activity or ATP-sensitive potassium channels. [1] |
| In vivo | BMS-199264 hydrochloride exhibited in an isolated rat heart ischemia model: hearts were pretreated with 3 μM BMS-199264 hydrochloride for 10 minutes before global ischemia. After 15 minutes of ischemia, mitochondrial F₁F₀ ATP synthase activity was measured, showing that BMS-199264 hydrochloride selectively inhibited hydrolase activity without affecting synthase function.[1] |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80 mg/mL (140.96 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (5.81 mM), Sonication is recommended. |
| Keywords | BMS-199264 Hydrochloride | BMS 199264 hydrochloride | BMS 199264 Hydrochloride |
| Inhibitors Related | Sodium oleate | DHQ | Ciclopirox | trans-Aconitic acid | Phlorizin | Ginsenoside Rb1 | Chlorpropamide | Esomeprazole Magnesium | Revaprazan hydrochloride | Oleic acid | Esomeprazole Sodium | Trichlormethiazide |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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