Product Details
| Product Name:
Candoxatril |
CAS No.:
123122-55-4 |
| Purity:
98.90% |
Supply Ability:
10g |
| Release date:
2025/11/10 |
Product Introduction
Bioactivity
| Name | Candoxatril |
| Description | Candoxatril (UK 79300) is an orally active neutral peptide endonuclease (NEP, EC 3.4.24.11) inhibitor that improves exercise capacity in patients with chronic heart failure undergoing angiotensin-converting enzyme inhibition. |
| In vivo | NEP inhibitors do not significantly affect body weight, food and water intake, mean blood pressure, or creatinine levels; however, they increase cGMP levels in urine and exhibit anti-inflammatory effects on hematopoiesis. Additionally, a-SMA deposition in the kidney cortex is inversely correlated with cGMP elevation [2]. |
| Storage | store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | UK-79300 | UK79300 | neutral endopeptidase (NEP) | NEP | Candoxatril |
| Inhibitors Related | LHW090-A7 | Sacubitril/Valsartan | Sacubitril sodium | Racecadotril | Sacubitril | NEP-IN-1 | SDUY816 | SDUY817 | Sacubitril hemicalcium salt | Thiorphan | Sacubitrilat | Phosphoramidon Disodium |
| Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | Anti-Cardiovascular Disease Compound Library | Metabolism Compound Library | Orally Active Compound Library | Bioactive Compounds Library Max | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$293.00/1mg |
VIP4Y
|
TargetMol Chemicals Inc.
|
2025-11-10 |
United States