Endothelin 1 (swine, human) NEW
| Price | $1410 |
| Package | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-02 |
Product Details
| Product Name: Endothelin 1 (swine, human) | CAS No.: 117399-94-7 |
| Supply Ability: 10g | Release date: 2025/12/02 |
Product Introduction
Bioactivity
| Name | Endothelin 1 (swine, human) |
| Description | Endothelin 1 (swine, human), a synthetic peptide mirroring the sequence of both human and swine Endothelin 1, functions as a robust endogenous vasoconstrictor by interacting with two receptor types, ETA and ETB. |
| In vitro | Endothelin-1 (ET-1), a potent endogenous vasoconstrictor primarily secreted by endothelial cells, operates via ETA and ETB receptors. Beyond its vasoconstrictive effect, ET-1 contributes to vascular cell fibrosis and prompts the generation of reactive oxygen species. Additionally, ET-1 is implicated in proinflammatory mechanisms by elevating superoxide anion output and cytokine release. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 50 mg/mL (20.07 mM), Sonication is recommended. |
| Keywords | ETA and ETB | Endothelin 1 (swine, human) | Endothelin 1 |
| Inhibitors Related | Macitentan | BMS 182874 | Bosentan | BMS 182874 hydrochloride | Sitaxsentan sodium | Edonentan | Sulfisoxazole | Ambrisentan | Aprocitentan | Sparsentan | Nebentan potassium | Clazosentan |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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United States