GSK-3β inhibitor 1 NEW
| Price | $58 | $139 | $222 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-14 |
Product Details
| Product Name: GSK-3β inhibitor 1 | CAS No.: 187325-53-7 |
| Purity: 99.40% | Supply Ability: 10g |
| Release date: 2026/07/14 |
Product Introduction
Bioactivity
| Name | GSK-3β inhibitor 1 |
| Description | GSK-3β inhibitor 1 is an inhibitor of GSK-3β( IC50 of 4.9 nM) and demonstrates high antidiabetic efficacy. |
| In vivo | GSK-3β inhibitor 1(compound 3a) inhibits GSK-3β with IC50 4.19 nM. In a cell-based assay 3a shows no significant leucocyte toxicity at 10 M and is moderately cytotoxic against A549 cells. Compound 3a demonstrated high antidiabetic efficacy in obese streptozotocin-treated rats improving glucose tolerance at a dose of 50 mg/kg body weight thus representing an interesting lead for further optimization. |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.13 mg/mL (14.08 mM), Solution. 10% DMSO+90% Saline : < 3.13 mg/mL (14.08 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. DMSO : 31.25 mg/mL (140.61 mM), Sonication is recommended. |
| Keywords | Inhibitor | inhibit | GSK-3β inhibitor 1 | GSK3β inhibitor 1 | GSK-3β | GSK-3beta inhibitor 1 | GSK-3b inhibitor 1 | GSK-3 | GSK3 | GSK 3β inhibitor 1 | Glycogen synthase kinase-3 | Glycogen synthase kinase 3 |
| Inhibitors Related | Cromolyn sodium | 4-Methyl-6-Methoxycoumarin | Indazole | GSK 3 Inhibitor IX | AT7519 | 5-Bromoindole | 4-Chloro-2'-bromoacetophenone | Ethyl linoleate | Ginsenoside Rg2 | GSK-3 Inhibitor 5 | (E/Z)-10-Hydroxy-2-decenoic acid | ROCK-IN-5 |
| Related Compound Libraries | Bioactive Compound Library | Antidepressant Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Neuroprotective Compound Library | Inhibitor Library | Stem Cell Differentiation Compound Library | Metabolism Compound Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Wnt/Hedgehog/Notch Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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