IT1t dihydrochloride NEW
| Price | $48 | $88 | $178 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-10 |
Product Details
| Product Name: IT1t dihydrochloride | CAS No.: 1092776-63-0 |
| Purity: 99.91% | Supply Ability: 10g |
| Release date: 2025/11/10 |
Product Introduction
Bioactivity
| Name | IT1t dihydrochloride |
| Description | IT1t dihydrochloride inhibits CXCL12/CXCR4 interaction with IC50 of 2.1 nM. IT1t dihydrochloride is an antagonist of CXCR4. |
| In vitro | AMD11070 shows antagonistic activity as it dose-dependently inhibits the CXCL12-induced intracellular calcium flux This calcium flux is inhibited by IT1t dihydrochloride with an IC50 of 23.1[1]. |
| In vivo | IT1t dihydrochloride reduces the formation of early metastases of TNBC in a zebrafish xenograft model. After CXCR4 silencing, tumor cell invasion at metastatic sites was effectively reduced [3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (2.09 mM), Sonication is recommended. DMSO : 27 mg/mL (56.3 mM), Sonication is recommended. |
| Keywords | IT-1t dihydrochloride | IT1t dihydrochloride | IT1t Dihydrochloride | IT1t | HIV-1 (X4) | CXCR4 | CXCL12/CXCR4 | CXCL12 |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Emtricitabine | Dolutegravir intermediate-1 | Lamivudine | Chloroquine phosphate | Probenecid | Valproic Acid | 3-Hydroxypyridine | Decanedioic acid | Dextran sulfate sodium salt (MW 5000) | Tenofovir |
| Related Compound Libraries | Bioactive Compound Library | Cytokine Inhibitor Library | Membrane Protein-targeted Compound Library | Hematonosis Compound Library | Autophagy Compound Library | Angiogenesis related Compound Library | Inhibitor Library | Immuno-Oncology Compound Library | PPI Inhibitor Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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