L-Azidonorleucine hydrochloride NEW
| Price | $31 |
| Package | 2mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-21 |
Product Details
| Product Name: L-Azidonorleucine hydrochloride | CAS No.: 1454334-76-9 |
| Supply Ability: 10g | Release date: 2025/08/21 |
Product Introduction
Bioactivity
| Name | L-Azidonorleucine hydrochloride |
| Description | L-Azidonorleucine hydrochloride, an unnatural amino acid, serves as a substitute for Methionine, and is used for labeling mammalian cell proteins and identifying various methionyl-tRNA synthetase (MetRS) mutants. |
| In vitro | CHO cells transfected with pMaRSC and incubated with L-Azidonorleucine (Anl; 1.5 mM; 6 h) are fixed, permeabilized, and treated with alkyne-TAMRA. The TAMRA fluorescence is observed exclusively in mCherry-expressing cells, indicating selective incorporation of Anl into cellular proteins[1]. |
| In vivo | When administering L-Azidonorleucine (ANL) through drinking water, it is recommended to maintain an intake of 0.9 mg/day/g body weight for 21 days to label specific brain neuronal populations. For other cell types, reduced dosages or shorter labeling durations may suffice. Alternatively, for intraperitoneal (i.p.) injection, exploring dosages between 4-400 mM is advised. Specifically, a 400 mM dose administered i.p. (10 ml/kg volume) daily for a week effectively labels certain neuronal populations, like the excitatory neurons in the hippocampus, whereas lower concentrations (e.g., 4 mM) are suitable for labeling different cell types or for extended labeling periods[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | L Azidonorleucine hydrochloride | L-Azidonorleucine Hydrochloride | LAzidonorleucine hydrochloride |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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