Product Details
| Product Name:
MCP110 |
CAS No.:
521310-51-0 |
| Purity:
97.23% |
Supply Ability:
10g |
| Release date:
2025/11/10 |
Product Introduction
Bioactivity
| Name | MCP110 |
| Description | MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors. |
| In vitro | In A549 cells, MCP110 (20 μM) decreases Ras stimulation of Raf-1 and cyclin D level stimulated by the treatment with EGF (100 ng/mL), platelet-derived growth factor (20 ng/mL), and serum. In in HEK293 cells, MCP110 (10 and 20 μM) inhibits H-Ras (V12)-induced AP-1 activation. In fibrosarcoma HT1080 cells, MCP110 (1, 2, 5, 10, and 20 μM) shows a dose-dependent inhibition of elevated Raf-1 activity[1]. |
| Storage | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5 mg/mL (9.83 mM), Sonication is recommended.
DMSO : 245 mg/mL (481.67 mM), Sonication is recommended.
|
| Keywords | Ras | Raf-1 | Raf kinases | Raf | MCP110 | Inhibitor | inhibit | colorectal | cancer | astrocytomas |
| Inhibitors Related | Adagrasib | BI-2493 | Regorafenib monohydrate | RMC-9805 | Sorafenib | Ketoconazole | MRTX1133 | RMC-6236 | Regorafenib | Dabrafenib | Sorafenib tosylate | N-Acetylneuraminic acid |
| Related Compound Libraries | Reprogramming Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | HIF-1 Signaling Pathway Compound Library | Kinase Inhibitor Library | Anti-Obesity Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States