Methyl pyropheophorbide-a NEW
| Price | $32 |
| Package | 1mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-26 |
Product Details
| Product Name: Methyl pyropheophorbide-a | CAS No.: 6453-67-4 |
| Purity: 98.17% | Supply Ability: 10g |
| Release date: 2025/10/26 |
Product Introduction
Bioactivity
| Name | Methyl pyropheophorbide-a |
| Description | Methyl pyropheophorbide-a (MPPa) is a chlorine photosensitizer and a derivative of chlorophyll a. It is photodynamically active, induces apoptosis and inhibits tumor growth, and can be used in photodynamic therapy (PDT) of cancer. |
| In vitro | In PC-3M cells, after treatment with Methyl pyropheophorbide-a (2 μM; 12 h) under LC75 conditions (2 μM + 55.6 kJ/m²), the apoptosis rates were approximately 0.27%, 6.15%, 20.49%, 50.76%, 65.39%, 64.92%, and 64.37% at 1, 3, 6, 12, 18, and 24 hours post-treatment, respectively[1]. |
| In vivo | In male BALB/c nude mice (6-8 weeks old, 16-20 g) bearing PC-3M tumors, Methyl pyropheophorbide-a (15 mg/kg; tail vein injection and topical injection) resulted in tumor volume and weight inhibition rates of 46.78% and 41.84% in the tail vein injection group, respectively, and 78.66% and 72.07% in the topical injection group, respectively[2]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 1 mg/mL (1.82 mM), Sonication is recommended. |
| Keywords | MPPa (Methyl pyropheophorbide-a) | Methyl pyropheophorbide-a | Methyl pyropheophorbidea | Methyl pyropheophorbide a | Apoptosis |
| Inhibitors Related | Stavudine | Cysteamine hydrochloride | Acetylcysteine | L-Glutamic acid monosodium salt monohydrate | Sodium 4-phenylbutyrate | L-Ascorbic acid | Metronidazole | L-Glutamic acid | Tributyrin | L-Ascorbic acid sodium salt | Alginic acid | Dextran sulfate sodium salt (MW 5000) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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