N-Acetyl lysyltyrosylcysteine amide NEW
| Price | $72 | $183 | $313 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-09 |
Product Details
| Product Name: N-Acetyl lysyltyrosylcysteine amide | CAS No.: 1287585-40-3 |
| Purity: 98.08% | Supply Ability: 10g |
| Release date: 2025/11/09 |
Product Introduction
Bioactivity
| Name | N-Acetyl lysyltyrosylcysteine amide |
| Description | N-Acetyl lysyltyrosylcysteine amide is a non-toxic, potent, reversible, and specific myeloperoxidase (MPO) tripeptide inhibitor that effectively inhibits MPO production in vivo, attenuates neuronal damage, preserves brain tissue and neurological function post-stroke, and inhibits MPO-dependent hypochlorite (HOCl) production, protein nitration, and LDL oxidation. It is also used in the study of bronchial dysplasia. |
| In vivo | N-Acetyl lysyltyrosylcysteine amide (KYC) (10 mg/kg; i.p.; daily for 3-7 days; C57BL/6J mice) significantly reduces neurological severity scores and infarct size in MCAO mice.[1] N-Acetyl lysyltyrosylcysteine amide (10 mg/kg; i.p.; daily for 7 days) significantly protects BBB function and decreased neutrophil infiltration.[1] N-Acetyl lysyltyrosylcysteine amide (10 mg/kg; i.p.; daily for 7 days; C57BL/6J mice) significantly reduces microglia/macrophage activation and neuron loss in MCAO mice.[1] N-Acetyl lysyltyrosylcysteine amide (10 mg/kg; i.p.; daily for 3-7 days; C57BL/6J mice) decreases apoptosis and cell injury in the brains of MCAO mice.[1] N-Acetyl lysyltyrosylcysteine amide reduced MPO in the brains of MCAO mice. N-Acetyl lysyltyrosylcysteine amide reduces NO2Tyr and 4-HNE in MCAO mice. N-Acetyl lysyltyrosylcysteine amide significantly decreases infarct size, blood-brain barrier leakage, infiltration of myeloid cells, loss of neurons, and apoptosis in the brains of middle cerebral artery occlusion (MCAO) mice.[1] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 55 mg/mL (121.26 mM), Sonication is recommended. |
| Keywords | N-Acetyl lysyltyrosylcysteine Amide | NAcetyl lysyltyrosylcysteine amide | N Acetyl lysyltyrosylcysteine amide | MPO | GlutathionePeroxidase | Glutathione Peroxidase |
| Inhibitors Related | AZD8309 | ML-210 | RSL3 | ML162 | PF-1355 | 5-Aminosalicylic Acid | Melatonin | 4-POBN | 4-Methylesculetin | Nabumetone | Cefdinir | GSTO1-IN-1 |
| Related Compound Libraries | Bioactive Compound Library | Glutamine Metabolism Compound Library | Peptide Compound Library | Inhibitor Library | Metabolism Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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