Pomalidomide-amido-C1-Br NEW
| Price | $169 |
| Package | 2mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-27 |
Product Details
| Product Name: Pomalidomide-amido-C1-Br | CAS No.: 2351106-38-0 |
| Supply Ability: 10g | Release date: 2025/10/27 |
Product Introduction
Bioactivity
| Name | Pomalidomide-amido-C1-Br |
| Description | Pomalidomide-amido-C1-Br is a synthesized conjugate consisting of the Pomalidomide-based cereblon ligand and a linker, functioning as an E3 ligase ligand-linker. This compound serves as a tool for designing a B-Raf PROTAC degrader, specifically PROTAC B-Raf degrader 1, which exhibits anti-cancer activity[1]. |
| In vitro | Pomalidomide-amido-C1-Br (Compound 6) serves as a precursor for synthesizing PROTAC B-Raf degrader 1 (Compound 2), an effective anticancer agent that induces apoptosis in cancer cells by accelerating B-Raf degradation via the ubiquitin-proteasome system, affecting Mcl-1 expression, a downstream protein associated with B-Raf, highlighting its mechanism of action[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Pomalidomide-amido-C1-Br | Pomalidomide-amido-C-1-Br | PomalidomideamidoC1Br | Pomalidomide amido C1 Br | Cereblon |
| Inhibitors Related | Pomalidomide-PEG4-Ph-NH2 | Thalidomide-O-amido-PEG2-C2-NH2 TFA | (S,R,S)-AHPC-PEG2-NH2 hydrochloride | Pomalidomide 4'-alkylC3-acid | Thalidomide-O-amido-C6-NH2 TFA | Thalidomide-O-amido-C6-NH2 hydrochloride | Pomalidomide-C2-acid | Thalidomide-propargyl | (S,R,S)-AHPC-PEG3-N3 | Pomalidomide 4'-PEG3-azide | Thalidomide-O-C6-NH2 hydrochloride | Thalidomide-O-amido-C4-NH2 TFA |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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