PRDX1-IN-1 NEW
| Price | $599 |
| Package | 1mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-09-11 |
Product Details
| Product Name: PRDX1-IN-1 | Purity: 98.04% |
| Supply Ability: 10g | Release date: 2025/09/11 |
Product Introduction
Bioactivity
| Name | PRDX1-IN-1 |
| Description | PRDX1-IN-1 is a selective and potent PRDX1 inhibitor with potential anti-inflammatory and anticancer activity for the study of breast and esophageal cancer. |
| In vitro | PRDX1-IN-1 (0.5-10 μM; 48 hours) was able to inhibit the proliferative activity of lung cancer cell lines (LTEP-a-2 and H1975), and human breast cancer cell line (MDA-MB-231)[1]. |
| In vivo | PRDX1-IN-1 (0.5 or 1 mg/kg; once daily for 19 days; intraperitoneal injection) treatment in C57BL/6J male mice inoculated with Lewis cells (lung cancer) was found to significantly inhibit tumor growth and induce morphological changes in tumor cells, including cell aggregation, contraction, and nuclear chromatin margination[1]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80 mg/mL (112.05 mM), Sonication is recommended. |
| Keywords | ROSKinase | ROS Kinase | PRDX1 |
| Inhibitors Related | Entrectinib | Lorlatinib | Taletrectinib | ROS kinases-IN-1 | Repotrectinib | Crizotinib hydrochloride | Iruplinalkib | Uniconazole | Crizotinib | F-1 | ROS kinases-IN-2 | ROS-generating agent 1 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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United States