Product Details
| Product Name:
SJB3-019A |
CAS No.:
2070015-29-9 |
| Purity:
99.75% |
Supply Ability:
10g |
| Release date:
2025/11/10 |
Product Introduction
Bioactivity
| Name | SJB3-019A |
| Description | SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 degradation and cytotoxicity in K562 cells 5 times more than SJB2-043, with IC50 of 0.0781 μM. SJB3-019A inhibits cell proliferation and causes cell apoptosis. |
| In vitro | SJB3-019A with IC50 of 0.0781 μM is 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells. SJB3-019A increases the levels of Ub-FANCD2 and Ub-PCNA, and decreases the HR activity. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 1 mg/mL (3.62 mM), Sonication is recommended.
|
| Keywords | USP1 | SJB3-019A | SJB-3-019A | SJB3019A | SJB3 019A | ID1 |
| Inhibitors Related | P22074 | BAY 11-7082 | USP15-IN-1 | N-Ethylmaleimide | DUB-IN-1 | USP30 inhibitor 11 | Vialinin A | GRL0617 | IMP-1710 | Spautin-1 | 6-Thioguanine | USP8-IN-3 |
| Related Compound Libraries | Apoptosis Compound Library | Bioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$95.00/1mg |
VIP6Y
|
TargetMol Chemicals Inc.
|
2025-11-10 |
United States