THP-PEG4-Pyrrolidine(N-Me)-CH2OH NEW
| Price | $39 |
| Package | 2mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-27 |
Product Details
| Product Name: THP-PEG4-Pyrrolidine(N-Me)-CH2OH | CAS No.: 2378261-81-3 |
| Supply Ability: 10g | Release date: 2025/10/27 |
Product Introduction
Bioactivity
| Name | THP-PEG4-Pyrrolidine(N-Me)-CH2OH |
| Description | THP-PEG4-Pyrrolidine(N-Me)-CH2OH, a PEG-based PROTAC linker, aids in the synthesis of PROTAC K-Ras Degrader-1[1]. |
| In vitro | PROTAC K-Ras Degrader-1 is a potent K-Ras degrader based on PROTAC, exhibiting ≥70% degradation efficacy in SW1573 cells[1]. PROTACs contain two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest, leveraging the ubiquitin-proteasome system for selective protein degradation. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | THP-PEG4-Pyrrolidine(N-Me)-CH2OH | THP-PEG-4-Pyrrolidine(N-Me)-CH2OH | THPPEG4Pyrrolidine(NMe)CH2OH | THP PEG4 Pyrrolidine(N Me) CH2OH | PEGs |
| Inhibitors Related | N-(4-Carboxycyclohexylmethyl)maleimide | Boc-C16-COOH | Pentaethylene glycol | Azido-PEG1 | Diethylene glycol bis(p-toluenesulfonate) | 6-Maleimidocapronic acid | Triethylene glycol | Bis-Tos-PEG4 | 11-Aminoundecanoic acid | 1,3-Dibromo-5,5-dimethylhydantoin | m-PEG12-NHS ester | Tetraethylene glycol |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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United States