Trimethylamine N-oxide dihydrate NEW
| Price | Get Latest Price |
| Package | 1removed |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-04 |
Product Details
| Product Name: Trimethylamine N-oxide dihydrate | CAS No.: 62637-93-8 |
| Purity: 98.75% | Supply Ability: 10g |
| Release date: 2025/11/04 |
Product Introduction
Bioactivity
| Name | Trimethylamine N-oxide dihydrate |
| Description | Trimethylamine N-oxide dihydrate (TMANO dihydrate) is a gut microbiota-dependent metabolite derived from dietary choline and other trimethylamine-containing nutrients. It induces inflammation by activating the ROS/NLRP3 inflammasome and promotes fibroblast differentiation and cardiac fibrosis via the TGF-β/Smad2 signaling pathway. TMANO dihydrate can be used to establish models of cardiac hypertrophy and cardiac fibrosis. |
| Storage | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (18 mM), Sonication is recommended. DMSO : 20 mg/mL (179.95 mM), Sonication is recommended. |
| Keywords | Trimethylamine N-oxide Dihydrate | Trimethylamine N-oxide dihydrate | Trimethylamine Noxide dihydrate | Trimethylamine N-oxide | Trimethylamine N oxide dihydrate | trimethylamine | Transforming growth factor beta | TMANO | TGF-βRI | TGF-beta/Smad | Smad2 | Reactive Oxygen Species | NOD-like Receptor (NLR) | myocardial | Microbe-dependent | metabolite | Inhibitor | inhibit | inflammation | fibrosis | EndogenousMetabolite | Endogenous Metabolite | dysfunction | choline | cardiac |
| Inhibitors Related | Sucrose | Cysteamine hydrochloride | D(+)-Raffinose pentahydrate | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid | Oxalic acid |
| Related Compound Libraries | Bioactive Compound Library | Natural Product Library | NO PAINS Compound Library | Cosmetic Ingredient Compound Library | Human Endogenous Metabolite Compound Library Plus | Bioactive Compounds Library Max | Gut Microbial Metabolite Library | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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