VEGFR-2-IN-9 NEW
| Price | $700 | $1800 |
| Package | 1mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-30 |
Product Details
| Product Name: VEGFR-2-IN-9 | CAS No.: 408502-06-7 |
| Purity: 97.19% | Supply Ability: 10g |
| Release date: 2025/06/30 |
Product Introduction
Bioactivity
| Name | VEGFR-2-IN-9 |
| Description | VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor with an IC50 of 7 nM, suitable for breast cancer research. |
| In vitro | One of the human tyrosine kinases with a high affinity for vascular endothelial growth factor (VEGF) is KDR (kinase insert domain-containing receptor), believed to be a primary mediator of tumor-induced angiogenesis[2]. |
| In vivo | KDR-in-4, at doses of 100 mg/kg, results in a 98% reduction in lesion size in the rat choroidal neovascularization (CNV) model, demonstrating potential utility for the treatment of various ocular neovascular diseases through a convenient oral dosing regimen. In the laser CNV and rat oxygen-induced retinopathy (OIR) models, 30 mg/kg doses of KDR-in-4 exhibit reductions in lesion size of 70% and 80%, respectively[1]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | VEGFR-2-IN-9 | VEGFR2 (KDR) | KDR |
| Inhibitors Related | Ribociclib | Nintedanib | Regorafenib monohydrate | Taxifolin | Sorafenib | Regorafenib | Sanguinarine chloride | Ponatinib | Sorafenib tosylate | Lenvatinib mesylate | Pazopanib | Axitinib |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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