ABOUT Berberine HCL
Detail of Organic Berberine Extract
Appearance: Yellow crystalline powder
Plant Source: Cortex Phellodendri Chinensis,
Function : antibacteria and anti-inflammatory , anti-hypertension . The treatment of intestinal infection such as bacterial dysentery and gastroenteritis and enhance body immunity .
Application : food additives , fishery , animal husbandry , organic pesticide and pharmaceuticals
Storage: in a cool dry place
Shelf Life: 2 years
Packing: 25kg/drum, double-layer plastic bags inside and fiber drum outside
Product Application
1) Berberine has been used clinically as an over-the-counter medicine for the treatment of diarrhea, but modern pharmacological studies have confirmed that berberine has significant anti-heart failure, anti-arrhythmic, lowering cholesterol, resistance to vascular smooth muscle proliferation, anti-platelet, Anti-inflammatory and other effects, so it may have a wide range of important application prospects in cardiovascular system and nervous system diseases, and it is being paid more and more attention.
2) In addition, because of its antibacterial and anti-inflammatory effects, berberine is involved in cosmetics, health products, and anti-inflammatory for external application. In recent years, its application and development have become more and more extensive.In addition to human medicine, food, cosmetics (special cosmetics, pharmaceutical cosmetics, etc.), veterinary medicine (chicken, duck, fish, shrimp), biological pesticides (instead of pesticides), protection for green plant and vegetable, in recent years, especially in Europe, America and Canada , Australia, New Zealand and other regions, medicines are also generally replaced by berberine, which is more environmentally friendly
Production Process
Purchase raw material vegetation (bark) Crushing workshop Powder raw material feeding Full Dissolving the target product with lytic enzyme Filtrating and separating Refining and purifying Drying Packing of the finished product
Production cycle: One cycle of soaking method usually needs 25-28 days.
Factory advantage
1. Complete and perfect equipment configuration:
1) For the reason that the soaking process involved, the amount of solvent in the production process is huge, and the workshop is equipped with an ethanol distillation recycling tower;
2) Six 6500-liter stainless steel refiner reactors, four 6500-liter enamel reactors;
3) Two 30-meter fully automatic countercurrent dissolution production lines;
4) As there is huge amount of steam involved in the distillation and a large amount of solvent recycling, the factory uses the steam uniformly distributed from the industrial park (normal steam pressure is 8 kg, which is 8 atmospheres), and the factory owned boiler is used in a small amount;
2. Cost advantages:
the origin of medicinal materials for the low purchase price
3. Huge Scale Production Workshop:
For the extraction of berberine, the factory owns 5,000 square meters infiltrating warehouses with the capacity to soak 80 tons of raw material one-time. When the raw materials are soaked until the bark is white (when the target product of berberine is fully dissolved in a solvent, usually ethanol, the original bark turning white means sufficient soaked), the soak liquid is concentrated, refined and purified, and dried (it can be delivered in the form of powder or not in the form of powder, up to the buyer’s request) to obtain the finished berberine.
4. Quality advantages : Certificate of Analysis （COA）
Product Name | Berberine HCL |
Batch Number | 20210320 | Package | 25kg/drum |
Sample Date | Mar. 20, 2021 | Report Date | Mar. 25, 2021 |
Standard of Inspection: Internal Quality Control Standard (Comply with CHP) |
Items | Standard | Results |
Appearance | Yellow Crystalline Powder | Conformed |
Berberine HCL | ≥ 97% | 98.03% |
Ash | ≤ 3.0% | 1.23% |
Loss on Drying | ≤ 12% | 9.87% |
Total Plate Count | ≤ 1000CFU/g | Confirmed |
Molds and Yeasts | ≤ 100CFU/g | Confirmed |
E. Coli | Negative | Negative |
The content difference between titrametric method and HPLC inspection is small. The content of palmatine and jatrorrhizine meets the standards of the Chinese Pharmacopoeia 2015, and the heavy metals meet the standard for export.
Certificate：
关键字： 盐酸黄连素;盐酸小檗碱;
Shanghai Exquisite Biochemical Co., Ltd. established in 2009, we are specializing in production and supply API and chemicals.