Description: Acid-PEG4-t-butyl ester is a PEG derivative containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Name: Acid-PEG4-t-butyl ester
CAS#: 1835759-85-7
Chemical Formula: C16H30O8
Exact Mass: 350.1941
Molecular Weight: 350.41
Elemental Analysis: C, 54.84; H, 8.63; O, 36.53
Synonym: Acid-PEG4-t-butyl ester
IUPAC/Chemical Name: 2,2-dimethyl-4-oxo-3,7,10,13,16-pentaoxanonadecan-19-oic acid
InChi Key: LXMHKDZTUDTSCT-UHFFFAOYSA-N
InChi Code: InChI=1S/C16H30O8/c1-16(2,3)24-15(19)5-7-21-9-11-23-13-12-22-10-8-20-6-4-14(17)18/h4-13H2,1-3H3,(H,17,18)
SMILES Code: O=C(OC(C)(C)C)CCOCCOCCOCCOCCC(O)=O
Appearance: Solid powder
Purity: >95% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
关键字: 1835759-85-7;t-butyl ester;PEG4;
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