Description: Alkannin is a natural compound, which can inhibit Hepatic Inflammation in Diabetic Db/Db Mice. Alkannin Inhibits the Development of Ovarian Cancer by Affecting miR-4461. Alkannin-Induced Oxidative DNA Damage Synergizes With PARP Inhibition to Cause Cancer-Specific Cytotoxicity. Alkannin displays tumor suppressive activity by initiating apoptosis. Alkannin inhibited the growth of PANC-1 cells via modulating miR-199a-Klotho node. During this process, mTOR and MEK/ERK pathways were blunted.
Name: Alkannin
CAS#: 517-88-4
Chemical Formula: C16H16O5
Exact Mass: 288.0998
Molecular Weight: 288.3
Elemental Analysis: C, 66.66; H, 5.59; O, 27.75
Synonym: (–)-Alkannin, NSC-94524, NSC94524. NSC 94524
IUPAC/Chemical Name: (S)-5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione
InChi Key: NEZONWMXZKDMKF-JTQLQIEISA-N
InChi Code: InChI=1S/C16H16O5/c1-8(2)3-4-10(17)9-7-13(20)14-11(18)5-6-12(19)15(14)16(9)21/h3,5-7,10,17-19H,4H2,1-2H3/t10-/m0/s1
SMILES Code: OC1=C2C(C(C=C([C@H](C/C=C(C)/C)O)C2=O)=O)=C(O)C=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
关键字： 23444-65-7;Alkannin;
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