产品属性：
产品名称 | 规格 | CAS号 | 型号 |
1-Methylhistamine (hydrochloride) | 10mM 25mg 50mg | 6481-48-7 | EY-Y0163480 |
Cas No.6481-48-7
别名 N/A
化学名 1-methyl-H-imidazole-4-ethanamine, dihydrochloride
分子式 C6H11N3?2HCl
分子量 198.1
溶解度 1mg/mL in ethanol, 20mg/mL in DMSO
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述：
1-Methylhistamine is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism.[1] It has been used as a biomarker of histaminergic system activity in the brains of Alzheimer’s disease patients as well as those with hypersomnia and other neurological conditions.[2] [3]
Reference:
[1]. Lindell, S.E., and Schayer, R.W. Metabolism of injected [14C] histamine in the kidney of the dog. Br.J.Pharmacol.Chemother. 13(1), 52-53 (1958).
[2]. Motawaj, M., Peoc'h, K., Callebert, J., et al. CSF levels of the histamine metabolite tele-methylhistamine are only slightly decreased in Alzheimer’s disease. J.Alzheimers Dis. 22(3), 861-871 (2010).
[3]. Dauvilliers, Y., Delallée, N., Jaussent, I., et al. Normal cerebrospinal fluid histamine and tele-methylhistamine levels in hypersomnia conditions. Sleep 35(10), 1359-1366 (2016).
关键字： 6481-48-7;C6H11N3?2HCl;1-Methylhistamine (h;
上海一研生物科技有限公司Shanghai yiyan bio-technology Co. Ltd.主要从事免疫学、分子生物学和常规生化试剂等为一体的科研产品销售企业，公司自成立以来，秉承""全心全意服务于科研工作者""的企业理念，立足生物科技领域，运用生物技术和科研试剂，发展现代生物科技，为各类大中小医院及其它医疗机构、高等院校、科研院所、企事业单位提供优质的产品，服务生物科技领域的科学研究人员。
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