Product Name:HIV Integrase Protein Inhibitor(1)
CAS No.:172546-75-7
Synonyms:HIV编码整合酶(IN)抑制剂多肽
Catalog No.:162P12
Brand:HongTide(上海鸿肽生物)
Description:HIV编码整合酶(IN)的有效抑制剂多肽,由6个氨基酸组成的多肽,该酶负责将 HIV DNA 整合到人类基因组中。HIV Integrase Protein Inhibitor(1)能抑制 IN 介导的 3' 加工和整合,IC 为 2 µM。 该肽对来自其他逆转录病毒如 HIV-2、猫免疫缺陷病毒和莫洛尼鼠白血病病毒的 IN 蛋白也有活性。 还发现它可以抑制分解反应,这表明这种六肽作用于 IN 的催化位点处或附近。
HIV encodes an effective inhibitor peptide of integrase (IN), a peptide composed of six amino acids, which is responsible for integrating HIV DNA into the human genome. HIV Integrate Protein Inhibitor (1) can inhibit IN mediated 3 'processing and integration, with an IC of 2 µ M. This peptide also has activity against IN proteins from other retroviruses such as HIV-2, feline immunodeficiency virus, and Moroni mouse leukemia virus. It was also found that it can inhibit the decomposition reaction, indicating that this hexapeptide acts at or near the catalytic site of IN.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | HCKFWW |
Sequence(3-letter code) | H-His-Cys-Lys-Phe-Trp-Trp-OH |
Peptide Structure |
|
Molecular Formula | C46H55N11O7S |
Molecular Weight | 906.07 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: 172546-75-7;HIV Integrase Protei;HIV编码整合酶(IN)抑制剂多肽?;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。