Product Name:ABT-510
CAS No.:251579-55-2
Synonyms:TSP-1模拟药物多肽
Catalog No.:218P133
Brand:HongTide(上海鸿肽生物)
Description:ABT-510是TSP-1模拟药物多肽,是一种由九个氨基酸组成的合成肽,它通过模拟内源性蛋白血小板反应蛋白-1(TSP-1)的抗血管生成活性发挥作用。ABT-510抑制对肿瘤新生血管形成重要的几种促血管生成生长因子的作用;这些促血管生成生长因子包括血管内皮生长因子(VEGF)、碱性成纤维细胞生长因子(bFGF)、肝细胞生长因子和白细胞介素8。ABT-510是以TSR为基础设计的,在新诊断的胶质母细胞瘤的一期临床试验中显示了抗血管生成财产。
ABT-510 is a TSP-1 mimetic drug peptide, which is a synthetic peptide composed of nine amino acids. It functions by simulating the anti angiogenic activity of the endogenous protein thrombospondin-1 (TSP-1). ABT-510 inhibits the effects of several important angiogenic growth factors on tumor neovascularization; These proangiogenic growth factors include vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), hepatocyte growth factor, and interleukin-8. ABT-510 is designed based on TSR and has shown anti angiogenic properties in the first phase clinical trial of newly diagnosed glioblastoma.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Ac-Sar-GV-D-allo-Ile-T-Nva-IRP-NHEt |
Sequence(3-letter code) | Ac-Sar-Gly-Val-D-allo-Ile-Thr-Nva-Ile-Arg-Pro-NHEt |
Peptide Structure |
|
Molecular Formula | C46H83N13O11 |
Molecular Weight | 994.23 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: 251579-55-2;ABT-510;TSP-1模拟药物多肽;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。